期刊
CHINESE JOURNAL OF NATURAL MEDICINES
卷 13, 期 6, 页码 471-480出版社
CHINESE JOURNAL NATURAL MEDICINES
DOI: 10.1016/S1875-5364(15)30042-X
关键词
Panax notoginseng powder; UPLC/Qtof MSE; Chemical fingerprint; Ginsenosides; Notoginsenosides
资金
- Science and Technology Program of Tianjin [12TXGCCX03800]
A method coupling ultra-performance liquid chromatography (UPLC) with quadrupole time-of-flight mass spectrometer (Qtof MS) using the electrospray ionization (ESI) source was developed for the identification of the major saponins from Panax notoginseng powder (PNP). Ten different PNP samples were analyzed and evaluated for their quality by similarity evaluation and principle component analysis (PCA). Based on the accurate mass, summarized characteristic fragmentation behaviors, retention times of different types of saponins, related botanical biogenesis, and reported chromatographic behavior of saponins, fifty-one common peaks were effectively separated and identified, including 28 protopanaxadiol saponins and 18 protopanaxatriol saponins. Simultaneously, 15 significant discrepancy compounds were identified from the disqualified PNP samples. The established UPLC/Qtof MS fingerprint method was successfully applied for profiling and identifying the major saponins of PNP, providing a fast quality evaluation tool for distinguishing the authentic PNP and the adulterated products.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据