期刊
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
卷 18, 期 6, 页码 481-489出版社
TAYLOR & FRANCIS AS
DOI: 10.1080/14737159.2018.1476141
关键词
Acute coronary syndrome; acute myocardial infarction; cardiac troponin T 5th generation; emergency department; high-sensitivity cardiac troponin
类别
Introduction: The Elecsys Troponin T Gen 5 STAT test (distributed in the United States (US) by Roche Diagnostics, Indianapolis, IN) is the first high-sensitivity cardiac troponin test approved for use by the FDA in the US (2017).Areas covered: The test offers clinicians the opportunity for more rapid decision-making for diagnosing myocardial infarction (MI) in the emergency department (ED). The Troponin T Gen 5 STAT test (labeled as TNT-G5ST on the reagent pack) is similar to the Troponin T hs STAT (TNT-HSST) and Troponin T hs (TNT-HS) tests that have been available outside the US since 2009. Collectively, these tests can all be considered as high-sensitivity cardiac troponin T (hs-cTnT) assays.Expert commentary: Studies performed in the US and throughout the world using 0 and 3h blood draws for hs-cTnT testing in patients with possible MI have reliably achieved a sensitivity of >94% and negative predictive value of 99% for MI in the ED setting.
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