期刊
CLINICAL PLASMA MEDICINE
卷 3, 期 1, 页码 17-23出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cpme.2015.02.001
关键词
Cold atmospheric pressure plasma; CAP; Decontamination infected cancer ulceration; Reduction microbial load; Wound healing; Medical plasma
This study is a retrospective review of representing clinical follow-up of 12 patients afflicted with advanced squamous cell carcinoma of the head and neck. Herein, we have used novel physical cold atmospheric pressure plasma (CAP) to decontaminate infected cancer ulcerations and evaluated anti-cancer effects. With use of CAP in this cohort, the data suggests: (1) decreased request for pain medication and (2) reduction of typical fetid odor related to (3) reduction of microbial load. In some cases there is (4) superficial partial remission of tumor and even (5) wound healing of infected ulcerations has been observed following CAP exposure. As a result, CAP treatment appears of benefit for select head and neck cancer patients and future work to optimize CAP in the therapeutic armamentarium advances. (C) 2015 Elsevier GmbH. All rights reserved.
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