相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate
Izna Ali et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Impact of concomitant medications on obstructive sleep apnoea
Ingrid Jullian-Desayes et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2017)
Allometric Scaling of Clearance in Paediatric Patients: When Does the Magic of 0.75 Fade?
Elisa A. M. Calvier et al.
CLINICAL PHARMACOKINETICS (2017)
Towards personalized treatment of pain using a quantitative systems pharmacology approach
Sebastiaan C. Goulooze et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Evidence-based drug treatment for special patient populations through model-based approaches
Elke H. J. Krekels et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Health Effects of Overweight and Obesity in 195 Countries over 25 Years
Ashkan Afshin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
The effect of morbid obesity on morphine glucuronidation
Celia Lloret-Linares et al.
PHARMACOLOGICAL RESEARCH (2017)
Use of Fentanyl in Adolescents with Clinically Severe Obesity Undergoing Bariatric Surgery: A Pilot Study
Janelle D. Vaughns et al.
PEDIATRIC DRUGS (2017)
Obesity and kidney disease: Hidden consequences of the epidemic
C. P. Kovesdy et al.
PHYSIOLOGY INTERNATIONAL (2017)
Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
Sjoerd de Hoogd et al.
CLINICAL PHARMACOKINETICS (2017)
Assessment of Glomerular Filtration Rate in Health and Disease: A State of the Art Review
A. S. Levey et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)
Pharmacokinetics of Clindamycin in Obese and Nonobese Children
Michael J. Smith et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Effect of Obesity on the Population Pharmacokinetics of Fluconazole in Critically Ill Patients
Abdulaziz S. Alobaid et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Population pharmacokinetics of oseltamivir and oseltamivir carboxylate in obese and non-obese volunteers
Kalayanee Chairat et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2016)
Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen
Anne van Rongen et al.
CLINICAL PHARMACOKINETICS (2016)
Trends in Obesity Among Adults in the United States, 2005 to 2014
Katherine M. Flegal et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Microdialysis as a way to measure antibiotics concentration in tissues
Sandrine Marchand et al.
PHARMACOLOGICAL RESEARCH (2016)
Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
Dong Dong et al.
DRUG METABOLISM AND DISPOSITION (2016)
Drug Disposition in Obesity: Toward Evidence-Based Dosing
Catherijne A. J. Knibbe et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)
Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical Practice
A. Smits et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents
Anne van Rongen et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Altered Morphine Glucuronide and Bile Acid Disposition in Patients With Nonalcoholic Steatohepatitis
B. C. Ferslew et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2015)
Targeting xenobiotic receptors PXR and CAR in human diseases
Monimoy Banerjee et al.
DRUG DISCOVERY TODAY (2015)
The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric Surgery
Margreke J. Brill et al.
PHARMACEUTICAL RESEARCH (2015)
Pharmacokinetics of Vancomycin in Extremely Obese Patients with Suspected or Confirmed Staphylococcus aureus Infections
Eyob D. Adane et al.
PHARMACOTHERAPY (2015)
Population pharmacodynamic model for low molecular weight heparin nadroparin in morbidly obese and non-obese patients using anti-Xa levels as endpoint
Jeroen Diepstraten et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2015)
New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition
Lori W. E. van der Schoor et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2015)
CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
Sarah J. Woolsey et al.
DRUG METABOLISM AND DISPOSITION (2015)
Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
Anika L. Dzierlenga et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Pharmacokinetics of Orally Administered Oseltamivir in Healthy Obese and Nonobese Thai Subjects
Podjanee Jittamala et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Midazolam Pharmacokinetics in Morbidly Obese Patients Following Semi-Simultaneous Oral and Intravenous Administration: A Comparison with Healthy Volunteers
Margreke J. E. Brill et al.
CLINICAL PHARMACOKINETICS (2014)
Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach
Celia Lloret-Linares et al.
CLINICAL PHARMACOKINETICS (2014)
Reduced subcutaneous tissue distribution of cefazolin in morbidly obese versus non-obese patients determined using clinical microdialysis
Margreke J. E. Brill et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)
2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society
Michael D. Jensen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Impact of OATP1B1, MDR1, and CYP3A4 Expression in Liver and Intestine on Interpatient Pharmacokinetic Variability of Atorvastatin in Obese Subjects
M. Ulvestad et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Obesity and the risk and outcome of infection
R. Huttunen et al.
INTERNATIONAL JOURNAL OF OBESITY (2013)
An Integrated Population Pharmacokinetic Meta-Analysis of Propofol in Morbidly Obese and Nonobese Adults, Adolescents, and Children
J. Diepstraten et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2013)
Intestinal permeability parameters in obese patients are correlated with metabolic syndrome risk factors
Tatiana F. S. Teixeira et al.
CLINICAL NUTRITION (2012)
Impact of Obesity on Drug Metabolism and Elimination in Adults and Children
Margreke J. E. Brill et al.
CLINICAL PHARMACOKINETICS (2012)
Maturation of the Glomerular Filtration Rate in Neonates, as Reflected by Amikacin Clearance
Roosmarijn F. W. De Cock et al.
CLINICAL PHARMACOKINETICS (2012)
Population pharmacokinetics of metformin in obese and non-obese patients with type 2 diabetes mellitus
Christophe Bardin et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Appropriate Chemotherapy Dosing for Obese Adult Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline
Jennifer J. Griggs et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Lean Body Weight Scalar for the Anesthetic Induction Dose of Propofol in Morbidly Obese Subjects
Jerry Ingrande et al.
ANESTHESIA AND ANALGESIA (2011)
Comparative evaluation of atracurium dosed on ideal body weight vs. total body weight in morbidly obese patients
Simone van Kralingen et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2011)
Obesity and Allometric Scaling of Pharmacokinetics
Douglas J. Eleveld et al.
CLINICAL PHARMACOKINETICS (2011)
Population Pharmacokinetics and Pharmacodynamics of Propofol in Morbidly Obese Patients
Simone van Kralingen et al.
CLINICAL PHARMACOKINETICS (2011)
Penetration of Anti-Infective Agents into Pulmonary Epithelial Lining Fluid Focus on Antibacterial Agents
Keith A. Rodvold et al.
CLINICAL PHARMACOKINETICS (2011)
Implications of Obesity for Drug Therapy: Limitations and Challenges
R. Jain et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Alteration of Hepatic but Not Renal Transporter Expression in Diet-Induced Obese Mice
Vijay R. More et al.
DRUG METABOLISM AND DISPOSITION (2011)
Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients
Martin G. Kees et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2011)
Oseltamivir pharmacokinetics in morbid obesity (OPTIMO trial)
L. M. Thorne-Humphrey et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2011)
On the Accuracy of Estimation of Basic Pharmacokinetic Parameters by the Traditional Noncompartmental Equations and the Prediction of the Steady-State Volume of Distribution in Obese Patients Based Upon Data Derived from Normal Subjects
Leonid M. Berezhkovskiy
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters
Romi Ghose et al.
LIFE SCIENCES (2011)
Impaired Pharmacokinetics of Levothyroxine in Severely Obese Volunteers
Marina A. Michalaki et al.
THYROID (2011)
Estimating the Glomerular Filtration Rate in Obese Adult Patients for Drug Dosing
Manjunath P. Pai
ADVANCES IN CHRONIC KIDNEY DISEASE (2010)
Effect of Obesity on the Pharmacokinetics of Drugs in Humans
Michael J. Hanley et al.
CLINICAL PHARMACOKINETICS (2010)
Estimation of creatinine clearance in morbidly obese patients
Jasmina A. Demirovic et al.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2009)
Should Dosing of Rocuronium in Obese Patients Be Based on Ideal or Corrected Body Weight?
Christian S. Meyhoff et al.
ANESTHESIA AND ANALGESIA (2009)
Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats
Craig D. Fisher et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery
April Barbour et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2009)
Hepatic microcirculation in fatty liver disease
Geoff C. Farrell et al.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2008)
Lean body mass normalizes the effect of obesity on renal function
Sarayut Janmahasatian et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Obesity-induced glomerular hyperfiltration: its involvement in the pathogenesis of tubular sodium reabsorption
Avry Chagnac et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2008)
Tissue concentrations: do we ever learn?
Johan W. Mouton et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)
Influence of morbid obesity on the single-dose pharmacokinetics of daptomycin
Manjunath P. Pai et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Pulmonary considerations in obesity and the bariatric surgical patient
Garth Davis et al.
MEDICAL CLINICS OF NORTH AMERICA (2007)
Association between nonalcoholic hepatic steatosis and hepatic cytochrome P-450 3A activity
Dhanashri Kolwankar et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)
Gastric emptying of solids and semi-solids in morbidly obese and non-obese subjects:: An assessment using the 13C-octanoic acid and 13C-acetic acid breath tests
Aloisio Cardoso-Junior et al.
OBESITY SURGERY (2007)
A pilot study testing whether concentrations of levofloxacin in interstitial space fluid of soft tissues may serve as a surrogate for predicting its pharmacokinetics in lung
Markus A. Zeitlinger et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2007)
Hepatic histology in obese patients undergoing bariatric surgery
Mariana Machado et al.
JOURNAL OF HEPATOLOGY (2006)
The effects of body mass index on lung volumes
Richard L. Jones et al.
CHEST (2006)
Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet
Kouichi Yoshinari et al.
PHARMACEUTICAL RESEARCH (2006)
Lean body mass-adjusted Cockcroft and Gault formula improves the estimation of glomerular filtration rate in subjects with normal-range serum creatinine
Wai H. Lim et al.
NEPHROLOGY (2006)
Estimating blood volume in obese and morbidly obese patients
HJM Lemmens et al.
OBESITY SURGERY (2006)
Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugs
M Brunner et al.
CURRENT OPINION IN PHARMACOLOGY (2005)
Predictors of nonalcoholic steatohepatitis and advanced fibrosis in morbidly obese patients
JP Ong et al.
OBESITY SURGERY (2005)
Quantification of lean bodyweight
S Janmahasatian et al.
CLINICAL PHARMACOKINETICS (2005)
What is the best size descriptor to use for pharmacokinetic studies in the obese?
B Green et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)
Alterations of gastrointestinal motility in obesity
JH Xing et al.
OBESITY RESEARCH (2004)
Bioavailability of hCG after intramuscular or subcutaneous injection in obese and non-obese women
CCW Chan et al.
HUMAN REPRODUCTION (2003)
CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
MG Emery et al.
HEPATOLOGY (2003)
The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers
GJ Sanderink et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Soft tissue concentrations of ciprofloxacin in obese and lean subjects following weight-adjusted dosing
UM Hollenstein et al.
INTERNATIONAL JOURNAL OF OBESITY (2001)