相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。27-Hydroxycholesterol suppresses lipid accumulation by down-regulating lipogenic and adipogenic gene expression in 3T3-L1 cells
Bungo Shirouchi et al.
CYTOTECHNOLOGY (2017)
Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients
Peter J. Crick et al.
MOLECULAR NEUROBIOLOGY (2017)
27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3
Zhaoxia Shen et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2017)
4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer
Francoise Gueraud
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Antioxidants and HNE in redox homeostasis
Wojciech Luczaj et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
4-hydroxynonenal-mediated signaling and aging
Hongqiao Zhang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Cancer growth regulation by 4-hydroxynonenal
Ana Cipak Gasparovic et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds
Brigitte M. Winklhofer-Roob et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Genotoxicity of lipid oxidation compounds
Peter M. Eckl et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases
Kamelija Zarkovic et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
HNE and cholesterol oxidation products in colorectal inflammation and carcinogenesis
Daniela Rossin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Proatherogenic effects of 4-hydroxynonenal
Anne Negre-Salvayre et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria
Mengqing Xiao et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds
Bebiana C. Sousa et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Immune oxysterols: Role in mycobacterial infection and inflammation
Saikou Y. Bah et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
Bile acid synthesis precursors in subjects with genetic hypercholesterolemia negative for LDLR/APOB/PCSK9/APOE mutations. Association with lipids and carotid atherosclerosis
L. Baila-Rueda et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD
Thomas Nury et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
Oxysterols formation: A review of a multifactorial process
Blanca Barriuso et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis
Takaya Nakazawa et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells
Yu An et al.
NEUROTOXICOLOGY (2017)
The Role of Oxysterols in Human Cancer
Alzbeta Kloudova et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice
Britta Noebauer et al.
JOURNAL OF DIABETES RESEARCH (2017)
Glycosyl chains and 25-hydroxycholesterol contribute to the intracellular transport of amyloid beta (Aβ-42) in Jurkat T cells
Neha Sharma et al.
FEBS OPEN BIO (2017)
Evolutionary Origin of the Interferon-Immune Metabolic Axis: The Sterol-Vitamin D Link
Harry Newmark et al.
FRONTIERS IN IMMUNOLOGY (2017)
7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptor
Hyok-rae Cho et al.
PLOS ONE (2017)
Exposure to atheroma-relevant 7-oxysterols causes proteomic alterations in cell death, cellular longevity, and lipid metabolism in THP-1 macrophages
Liam J. Ward et al.
PLOS ONE (2017)
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Gurdeep Marwarha et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2017)
Outside-in, inside-out: Proteomic analysis of endothelial stress mediated by 7-ketocholesterol
Livia Rosa-Fernandes et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2017)
Association of Plasma 7-Ketocholesterol With Cardiovascular Outcomes and Total Mortality in Patients With Coronary Artery Disease
Jiayi Song et al.
CIRCULATION RESEARCH (2017)
Simultaneous GC-MS/MS measurement of malondialdehyde and 4-hydroxy-2-nonenal in human plasma: Effects of long-term L-arginine administration
Dimitrios Tsikas et al.
ANALYTICAL BIOCHEMISTRY (2017)
CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer
Mahmoud A. Alfaqih et al.
CANCER RESEARCH (2017)
Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue
F. Kreilaus et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2016)
Tick-borne encephalitis - lipid peroxidation and its consequences
Wojciech Luczaj et al.
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2016)
25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase
Zhi-Jun Ou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2016)
Oxysterols: Old Tale, New Twists
Winnie Luu et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)
27-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells
Li-Ming Ma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Cholesterol oxidation products and their biological importance
Waldemar Kulig et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2016)
Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease
Margaux Doria et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
The onset of lipid peroxidation in rheumatoid arthritis: consequences and monitoring
Wojciech Luczaj et al.
FREE RADICAL RESEARCH (2016)
Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells
Meryam Debbabi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Formation of Malondialdehyde, 4-Hydroxynonenal, and 4-Hydroxyhexenal during in Vitro Digestion of Cooked Beef, Pork, Chicken, and Salmon
Christina Steppeler et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016)
Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis
Hua-Long Wang et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Free Radical-derived Oxysterols: Novel Adipokines Modulating Adipogenic Differentiation of Adipose Precursor Cells
Giuseppe Murdolo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
The role of oxysterols in vascular ageing
Simona Gargiulo et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
New methods for analysis of oxysterols and related compounds by LC-MS
William J. Griffiths et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
Relationship between oxysterols and mild cognitive impairment in the elderly: a case-control study
Quanri Liu et al.
LIPIDS IN HEALTH AND DISEASE (2016)
27-Hydroxycholesterol stimulates cell proliferation and resistance to docetaxel-induced apoptosis in prostate epithelial cells
Shaneabbas Raza et al.
MEDICAL ONCOLOGY (2016)
Oxysterols: An emerging class of broad spectrum antiviral effectors
David Lembo et al.
MOLECULAR ASPECTS OF MEDICINE (2016)
Oxysterols and mechanisms of survival signaling
Beyza Vurusaner et al.
MOLECULAR ASPECTS OF MEDICINE (2016)
Oxysterols: From cholesterol metabolites to key mediators
Valentin Mutemberezi et al.
PROGRESS IN LIPID RESEARCH (2016)
The ROS-mediated activation of STAT-3/VEGF signaling is involved in the 27-hydroxycholesterol-induced angiogenesis in human breast cancer cells
Dongmei Zhu et al.
TOXICOLOGY LETTERS (2016)
The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response
Michael B. Fessler
TRENDS IN IMMUNOLOGY (2016)
Oxysterols in Metabolic Syndrome: From Bystander Molecules to Bioactive Lipids
Owein Guillemot-Legris et al.
TRENDS IN MOLECULAR MEDICINE (2016)
Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer
Rebecca Swan et al.
ONCOTARGET (2016)
Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation
Gabriella Testa et al.
REDOX BIOLOGY (2016)
RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages
Zewen Kelvin Tuong et al.
PLOS ONE (2016)
Formation of reactive aldehydes (MDA, HHE, HNE) during the digestion of cod liver oil: comparison of human and porcine in vitro digestion models
Cecilia Tullberg et al.
FOOD & FUNCTION (2016)
Formation of malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE) and 4-hydroxy-2-nonenal (HNE) in fish and fish oil during dynamic gastrointestinal in vitro digestion
Karin Larsson et al.
FOOD & FUNCTION (2016)
Relation between TLR4/NF-B signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability
Simona Gargiulo et al.
AGING CELL (2015)
7α-Hydroxycholesterol induces inflammation by enhancing production of chemokine (C-C motif) ligand 2
Sun-Mi Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
27-Oxygenated cholesterol induces expression of CXCL8 in macrophages via NF-κB and CD88
Sun-Mi Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Oxidative Stress in COPD: Molecular Background and Clinical Monitoring
Balazs Antus et al.
CURRENT MEDICINAL CHEMISTRY (2015)
Oxidative stress: Determination of 4-hydroxy-2-nonenal by gas chromatography/mass spectrometry in human and rat plasma
S. Zelzer et al.
FREE RADICAL RESEARCH (2015)
Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation
Anggakusuma et al.
HEPATOLOGY (2015)
Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology
Marie-Anne Burlot et al.
HUMAN MOLECULAR GENETICS (2015)
Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages
Etimad A. Huwait et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Postprandial Dysmetabolism and Oxidative Stress in Type 2 Diabetes: Pathogenetic Mechanisms and Therapeutic Strategies
Barbara Sottero et al.
MEDICINAL RESEARCH REVIEWS (2015)
Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3)
Amira Zarrouk et al.
STEROIDS (2015)
Oxysterols: Influence on plasma membrane rafts microdomains and development of ocular diseases
Rodolphe Filomenko et al.
STEROIDS (2015)
Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis
Hongjin Lu et al.
STEROIDS (2015)
Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human
Marie Tremblay-Franco et al.
STEROIDS (2015)
Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)
Thomas Nury et al.
STEROIDS (2015)
Oxidized cholesterol as the driving force behind the development of Alzheimer's disease
Paola Gamba et al.
FRONTIERS IN AGING NEUROSCIENCE (2015)
Twin peaks: Searching for 4-hydroxynonenal urinary metabolites after oral administration in rats
Julia Keller et al.
REDOX BIOLOGY (2015)
4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation Product
Rudolf J. Schaur et al.
BIOMOLECULES (2015)
Involvement of oxysterols in age-related diseases and ageing processes
Amira Zarrouk et al.
AGEING RESEARCH REVIEWS (2014)
Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages
Inga Preuss et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs
Fumiyuki Nakagawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP
Masashi Iwamoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha
Michihisa Umetani et al.
CELL METABOLISM (2014)
The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol
Wan-Ru Lee et al.
CLINICAL LIPIDOLOGY (2014)
The initial characteristics of marine oil emulsions and the composition of the media inflect lipid oxidation during in vitro gastrointestinal digestion
Hernan Brice Kenmogne-Domguia et al.
FOOD CHEMISTRY (2014)
Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation
Irundika H. K. Dias et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Regulation and therapeutic strategies of 4-hydroxy-2-nonenal metabolism in heart disease
V. R. Mali et al.
FREE RADICAL RESEARCH (2014)
The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: New players in cholesterol metabolism
Maria Calderon-Dominguez et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
De Novo Synthesis of Steroids and Oxysterols in Adipocytes
Jiehan Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
Antonio Ayala et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation
Pejman Soroosh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling
Elizabeth S. Gold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon
Andrea Reboldi et al.
SCIENCE (2014)
27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes
Sun-Mi Kim et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Cholesterol and breast cancer pathophysiology
Erik R. Nelson et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol
Andrea Civra et al.
SCIENTIFIC REPORTS (2014)
27-Hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages
Sun-Mi Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
The association between biomarkers in the blood and carotid plaque composition-focusing on oxidized lipids, oxysterols and plaque status
Jacob Vaya
BIOCHEMICAL PHARMACOLOGY (2013)
Oxysterols in cancer cell proliferation and death
Jan de Weille et al.
BIOCHEMICAL PHARMACOLOGY (2013)
On the formation and possible biological role of 25-hydroxycholesterol
Ulf Diczfalusy
BIOCHIMIE (2013)
Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking
Yasuomi Urano et al.
FASEB JOURNAL (2013)
Lipokines and oxysterols: Novel adipose-derived lipid hormones linking adipose dysfunction and insulin resistance
Giuseppe Murdolo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol
Su-Yang Liu et al.
IMMUNITY (2013)
The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
Mathieu Blanc et al.
IMMUNITY (2013)
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
Laura Raccosta et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Sterols and oxysterols in immune cell function
Nathanael J. Spann et al.
NATURE IMMUNOLOGY (2013)
25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line
Sabine Waltl et al.
NEUROSCIENCE LETTERS (2013)
4-Hydroxyhexenal- and 4-Hydroxynonenal-Modified Proteins in Pterygia
Ichiya Sano et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation
Atsushi Ishikado et al.
PLOS ONE (2013)
27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth
Qian Wu et al.
CELL REPORTS (2013)
Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease
Sarah J. Chapple et al.
REDOX BIOLOGY (2013)
4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies
Marzia Perluigi et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n-3 polyunsaturated fatty acids
Ethan J. Anderson et al.
BIOCHEMICAL JOURNAL (2012)
Side-chain oxysterols: From cells to membranes to molecules
Brett N. Olsen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases
Huiyong Yin et al.
FREE RADICAL RESEARCH (2012)
Alteration of Some Inflammatory Biomarkers by Dietary Oxysterols in Rats
Ida Soto-Rodriguez et al.
INFLAMMATION (2012)
Roles of 7-ketocholesterol on the Homeostasis of Intracellular Cholesterol Level
Yonghae Son et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2012)
ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation
Elizabeth S. Gold et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells
Manar Awada et al.
JOURNAL OF LIPID RESEARCH (2012)
Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression
Melissa A. Bradley et al.
NEUROBIOLOGY OF AGING (2012)
Increased appearance rate of 27-hydroxycholesterol in vivo in hypercholesterolemia: A possible compensatory mechanism
M. Bertolotti et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2012)
Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase
Saloni Gill et al.
CELL METABOLISM (2011)
Oxysterols and calcium signal transduction
John J. Mackrill
CHEMISTRY AND PHYSICS OF LIPIDS (2011)
Oxysterols formation as a reflection of biochemical pathways: summary of in vitro and in vivo studies
Jacob Vaya et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2011)
Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands
Philippe de Medina et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2011)
Pathways of cholesterol oxidation via non-enzymatic mechanisms
Luigi Iuliano
CHEMISTRY AND PHYSICS OF LIPIDS (2011)
Oxysterols in bile acid metabolism
Andrea Crosignani et al.
CLINICA CHIMICA ACTA (2011)
New Insights into Redox-Modulated Cell Signaling
Gabriella Leonarduzzi et al.
CURRENT PHARMACEUTICAL DESIGN (2011)
Fate in digestion in vitro of several food components, including some toxic compounds coming from omega-3 and omega-6 lipids
Encarnacion Goicoechea et al.
FOOD AND CHEMICAL TOXICOLOGY (2011)
Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions
Simona Gargiulo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Mechanisms of oxysterol-induced carcinogenesis
Apinya Jusakul et al.
LIPIDS IN HEALTH AND DISEASE (2011)
Oxysterols direct immune cell migration via EBI2
Sebastien Hannedouche et al.
NATURE (2011)
The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes
Rosamaria Lappano et al.
PLOS ONE (2011)
Subgram daily supplementation with docosahexaenoic acid protects low-density lipoproteins from oxidation in healthy men
Catherine Calzada et al.
ATHEROSCLEROSIS (2010)
Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells
Atsushi Ishikado et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Oxysterols: A world to explore
A. Otaegui-Arrazola et al.
FOOD AND CHEMICAL TOXICOLOGY (2010)
Trans-4-hydroxy-2-hexenal, a product of n-3 fatty acid peroxidation: Make some room HNE ...
Eric K. Long et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease Implications for Aβ accumulation in AD brain
Joshua B. Owen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Oxysterols in biological systems: The gastrointestinal tract, liver, vascular wall and central nervous system
Christophe Garenc et al.
FREE RADICAL RESEARCH (2010)
Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands
Yongjun Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Scientific Opinion on Fish Oil for Human Consumption. Food Hygiene, including Rancidity
John Daniel Collins et al.
EFSA JOURNAL (2010)
Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: A potential mechanism of inflammatory bowel disease progression
Fiorella Biasi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Lipid peroxidation: Physiological levels and dual biological effects
Etsuo Niki
FREE RADICAL BIOLOGY AND MEDICINE (2009)
High levels of retinal membrane docosahexaenoic acid increase susceptibility to stress-induced degeneration
Masaki Tanito et al.
JOURNAL OF LIPID RESEARCH (2009)
Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments
Markus Griesser et al.
JOURNAL OF LIPID RESEARCH (2009)
Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis
Anne Vejux et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2009)
Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases
Sinead Lordan et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2009)
Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis
Andrew J. Brown et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
Interactions of oxysterols with membranes and proteins
Vesa M. Olkkonen et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages
Daniel Toeroecsik et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
Oxysterols and neurodegenerative diseases
Ingemar Bjorkhem et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production
David R. Bauman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis
A. Vejux et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2008)
Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase
Russell A. DeBose-Boyd
CELL RESEARCH (2008)
Use of an in vitro digestion model to study the bioaccessibility of 4-hydroxy-2-nonenal and related aldehydes present in oxidized oils rich in omega-6 acyl groups
Encarnacion Goicoechea et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Cholesterol, reactive oxygen species, and the formation of biologically active mediators
Robert C. Murphy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation
Eric K. Long et al.
JOURNAL OF NEUROCHEMISTRY (2008)
4-hydroxynonenal: A membrane lipid oxidation product of medicinal interest
G. Poli et al.
MEDICINAL RESEARCH REVIEWS (2008)
Purified NPC1 protein - I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein
Rodney E. Infante et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
4-hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation
Jennifer Whitsett et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Resolvin E1 and protectin D1 activate inflammation-resolution programmes
Jan M. Schwab et al.
NATURE (2007)
Oxysterols are substrates for cholesterol sulfotransferase
Hirotoshi Fuda et al.
JOURNAL OF LIPID RESEARCH (2007)
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
Arun Radhakrishnan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)
Jeffrey D. Coleman et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation
Sarah J. Siegel et al.
BIOCHEMISTRY (2007)
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ
Serena Ghisletti et al.
MOLECULAR CELL (2007)
NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols
Heng-Ling Liou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Distribution, interconversion, and dose response of n-3 fatty acids in humans
Linda M. Arterburn et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes
L Gil et al.
FREE RADICAL RESEARCH (2006)
Membrane and protein interactions of oxysterols
John B. Massey
CURRENT OPINION IN LIPIDOLOGY (2006)
The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis
I Staprans et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2005)
Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina
M Tanito et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Lead exposure and (n-3) fatty acid deficiency during rat neonatal development alter liver, plasma, and brain polyunsaturated fatty acid composition
SY Lim et al.
JOURNAL OF NUTRITION (2005)
Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells
S Choudhary et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
7-ketocholesterol favors lipid accumulation and colocalizes with nile red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis:: Analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation
A Vejux et al.
CYTOMETRY PART A (2005)
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages - Activation by oxidatively modified LDL and 4-hydroxynonenal
T Ishii et al.
CIRCULATION RESEARCH (2004)
Induction of endothelial iNOS by 4-hydroxyhexenal through NF-κb activation
JY Lee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses
S Bacot et al.
JOURNAL OF LIPID RESEARCH (2003)
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers
V Leoni et al.
JOURNAL OF LIPID RESEARCH (2003)
Metabolism of 4β-hydroxycholesterol in Humans
K Bodin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Measurement of 4-hydroxynonenal in small volume blood plasma samples: modification of a gas chromatographic-mass spectrometric method for clinical settings
D Spies-Martin et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2002)
The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease
ML Selley et al.
NEUROBIOLOGY OF AGING (2002)
Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells
S Choudhary et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Detection of 1,N2-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal after gavage of trans-4-hydroxy-2-nonenal or induction of lipid peroxidation with carbon tetrachloride in F344 rats
M Wacker et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2001)
Involvement of lipid peroxidation in spontaneous pancreatitis in WBN/Kob rats
F Furukawa et al.
PANCREAS (2001)
Involvement of aldose reductase in the metabolism of atherogenic aldehydes
S Srivastava et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2001)
4-hydroxynonenal in the pathomechanisms of oxidative stress
G Poli et al.
IUBMB LIFE (2000)