期刊
EPIDEMIOLOGY AND INFECTION
卷 146, 期 6, 页码 747-756出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268818000596
关键词
Group A Streptococcus; influenza; point-of-care; QUADAS; Streptococcus pneumonia; STARD
资金
- Memorial University of Newfoundland
Commercial point-of-care (POC) diagnostic tests for Group A Streptococcus, Streptococcus pneumoniae, and influenza virus have large potential diagnostic and financial impact. Many published reports on test performance, often funded by diagnostics companies, are prone to bias. The Standards for Reporting of Diagnostic Accuracy (STARD 2015) are a protocol to encourage accurate, transparent reporting. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool evaluates risk of bias and transportability of results. We used these tools to evaluate diagnostic test accuracy studies of POC studies for three respiratory pathogens. For the 96 studies analysed, compliance was <25% for 14/34 STARD 2015 standards, and 3/7 QUADAS-2 domains showed a high risk of bias. All reports lacked reporting of at least one criterion. These biases should be considered in the interpretation of study results.
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