相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Advances in the management of MEN2: from improved surgical and medical treatment to novel kinase inhibitors
Samuel A. Wells
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Advances in risk-oriented surgery for multiple endocrine neoplasia type 2
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ENDOCRINE-RELATED CANCER (2018)
A comprehensive review on MEN2B
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Patient quality of life and prognosis in multiple endocrine neoplasia type 2
Joanna Grey et al.
ENDOCRINE-RELATED CANCER (2018)
Structure and function of RET in multiple endocrine neoplasia type 2
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ENDOCRINE-RELATED CANCER (2018)
Genetic landscape of papillary thyroid carcinoma in the Chinese population
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JOURNAL OF PATHOLOGY (2018)
Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes
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NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Long-term outcome of prophylactic thyroidectomy in children carrying &ITRET&IT germline mutations
A. Machens et al.
BRITISH JOURNAL OF SURGERY (2018)
Novel targeted therapeutics for MEN2
Sara Redaelli et al.
ENDOCRINE-RELATED CANCER (2018)
Clinical and Translational Implications of RET Rearrangements in Non-Small Cell Lung Cancer
Roberto Ferrara et al.
JOURNAL OF THORACIC ONCOLOGY (2018)
RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients
Shumei Kato et al.
CLINICAL CANCER RESEARCH (2017)
Differential roles of RET isoforms in medullary and papillary thyroid carcinomas
Eric Y. Lian et al.
ENDOCRINE-RELATED CANCER (2017)
Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative
Vishnu Muthuraj Kumarasamy et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Differential recruitment of E3 ubiquitin ligase complexes regulates RET isoform internalization
Brandy D. Hyndman et al.
JOURNAL OF CELL SCIENCE (2017)
Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma
Gilbert J. Cote et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Medullary Thyroid Carcinoma in MEN2A: ATA Moderate- or High-Risk RET Mutations Do Not Predict Disease Aggressiveness
Rachel K. Voss et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Risk Profile of the RET A883F Germline Mutation: An International Collaborative Study
Jes Sloth Mathiesen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry
Oliver Gautschi et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Biology of GDNF and its receptors - Relevance for disorders of the central nervous system
Carlos F. Ibanez et al.
NEUROBIOLOGY OF DISEASE (2017)
Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma
M. Amit et al.
ONCOGENE (2017)
Lineage-dependent spatial and functional organization of the mammalian enteric nervous system
Reena Lasrado et al.
SCIENCE (2017)
Nationwide French Study of RET Variants Detected from 2003 to 2013 Suggests a Possible Influence of Polymorphisms as Modifiers
Maylis Lebeault et al.
THYROID (2017)
Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial
Kiyotaka Yoh et al.
LANCET RESPIRATORY MEDICINE (2017)
Overall survival analysis of EXAM, a phase III trial of cabozantinib in patients with radiographically progressive medullary thyroid carcinoma
M. Schlumberger et al.
ANNALS OF ONCOLOGY (2017)
Elevated RET expression enhances EGFR activation and mediates EGFR inhibitor resistance in head and neck squamous cell carcinoma
Chengzhong Lin et al.
CANCER LETTERS (2016)
Treatment of advanced thyroid cancer with targeted therapies: ten years of experience
David Viola et al.
ENDOCRINE-RELATED CANCER (2016)
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity
Rebecca Newton et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers
Rana Hatem et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma
Cristina Romei et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts
Elena Andreucci et al.
ONCOTARGET (2016)
Molecular Characterization of Inflammatory Myofibroblastic Tumors With Frequent ALK and ROS1 Gene Fusions and Rare Novel RET Rearrangement
Cristina R. Antonescu et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2015)
Preclinical Efficacy and Safety Assessment of an Antibody-Drug Conjugate Targeting the c-RET Proto-Oncogene for Breast Carcinoma
Minh Nguyen et al.
CLINICAL CANCER RESEARCH (2015)
Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo
Cynthia C. Tsui et al.
JOURNAL OF NEUROSCIENCE (2015)
Systemic and CNS activity of the RET inhibitor vandetanib combined with the mTOR inhibitor everolimus in KIF5B-RET re-arranged non-small cell lung cancer with brain metastases
Vivek Subbiah et al.
LUNG CANCER (2015)
The modifier role of RET-G691S polymorphism in hereditary medullary thyroid carcinoma: functional characterization and expression/penetrance studies
Carla Colombo et al.
ORPHANET JOURNAL OF RARE DISEASES (2015)
Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma
Samuel A. Wells et al.
THYROID (2015)
Comprehensive assessment of the disputed RET Y791F variant shows no association with medullary thyroid carcinoma susceptibility
Rodrigo A. Toledo et al.
ENDOCRINE-RELATED CANCER (2015)
Surgical Curability of Medullary Thyroid Cancer in Multiple Endocrine Neoplasia 2B A Changing Perspective
Michael Brauckhoff et al.
ANNALS OF SURGERY (2014)
Role of RET genetic variants in MEN2-associated pheochromocytoma
Debora Rodrigues Siqueira et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2014)
The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function
Diogo Fonseca-Pereira et al.
NATURE (2014)
ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation
F. Kosari et al.
ONCOGENE (2014)
The landscape of kinase fusions in cancer
Nicolas Stransky et al.
NATURE COMMUNICATIONS (2014)
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
Thomas Wiesner et al.
NATURE COMMUNICATIONS (2014)
RET revisited: expanding the oncogenic portfolio
Lois M. Mulligan
NATURE REVIEWS CANCER (2014)
Structural studies of GDNF family ligands with their receptors-Insights into ligand recognition and activation of receptor tyrosine kinase RET
Xinquan Wang
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)
RET/PTC and PAX8/PPAR chromosomal rearrangements in post-Chernobyl thyroid cancer and their association with iodine-131 radiation dose and other characteristics
Rebecca J. Leeman-Neill et al.
CANCER (2013)
GDNF-RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors
Andrea Morandi et al.
CANCER RESEARCH (2013)
Vandetanib in Children and Adolescents with Multiple Endocrine Neoplasia Type 2B Associated Medullary Thyroid Carcinoma
Elizabeth Fox et al.
CLINICAL CANCER RESEARCH (2013)
Ret inhibition decreases growth and metastatic potential of estrogen receptor positive breast cancer cells
Albana Gattelli et al.
EMBO MOLECULAR MEDICINE (2013)
Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells
Matti L. Gild et al.
ENDOCRINE-RELATED CANCER (2013)
High penetrance of pheochromocytoma in multiple endocrine neoplasia 2 caused by germ line RET codon 634 mutation in Japanese patients
Tsuneo Imai et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2013)
Pharmacokinetic evaluation of cabozantinib for the treatment of thyroid cancer
Spyridon Karras et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
Novel tandem germline RET proto-oncogene mutations in a patient with multiple endocrine neoplasia type 2B: Report of a case and a literature review of tandem RET mutations with in silico analysis
Kanako-Tanase Nakao et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2013)
The involvement of the RET variant G691S in medullary thyroid carcinoma enlightened by a meta-analysis study
Francesca Lantieri et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Cabozantinib in Progressive Medullary Thyroid Cancer
Rossella Elisei et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
RET is a potential tumor suppressor gene in colorectal cancer
Y. Luo et al.
ONCOGENE (2013)
Structure and Physiology of the RET Receptor Tyrosine Kinase
Carlos F. Ibanez
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas
Alexander Drilon et al.
CANCER DISCOVERY (2013)
Molecular pathogenesis and mechanisms of thyroid cancer
Mingzhao Xing
NATURE REVIEWS CANCER (2013)
The rearranged during transfection/papillary thyroid carcinoma tyrosine kinase is an estrogen-dependent gene required for the growth of estrogen receptor positive breast cancer cells
Chunyu Wang et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Additive effect of RET polymorphisms on sporadic medullary thyroid carcinoma susceptibility and tumor aggressiveness
Lucieli Ceolin et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2012)
Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial
Samuel A. Wells et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation
P. Ballerini et al.
LEUKEMIA (2012)
KIF5B-RET fusions in lung adenocarcinoma
Takashi Kohno et al.
NATURE MEDICINE (2012)
RET protein expression in papillary renal cell carcinoma
Richard Flavin et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2012)
RET genetic screening of sporadic medullary thyroid cancer (MTC) allows the preclinical diagnosis of unsuspected gene carriers and the identification of a relevant percentage of hidden familial MTC (FMTC)
C. Romei et al.
CLINICAL ENDOCRINOLOGY (2011)
Multiple Endocrine Neoplasia Type 2B with a RET Proto-Oncogene A883F Mutation Displays a More Indolent Form of Medullary Thyroid Carcinoma Compared with a RET M918T Mutation
Sina Jasim et al.
THYROID (2011)
RET in breast cancer: functional and therapeutic implications
Andrea Morandi et al.
TRENDS IN MOLECULAR MEDICINE (2011)
RET Is a Heat Shock Protein 90 (HSP90) Client Protein and Is Knocked Down upon HSP90 Pharmacological Block
Luigi Alfano et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
High Penetrance of Pheochromocytoma Associated with the Novel C634Y/Y791F Double Germline Mutation in the RET Protooncogene
Rodrigo A. Toledo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Paracrine Regulation of Pancreatic Cancer Cell Invasion by Peripheral Nerves
Ziv Gil et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance
I. Plaza-Menacho et al.
ONCOGENE (2010)
Correlation of RET somatic mutations with clinicopathological features in sporadic medullary thyroid carcinomas
M. M. Moura et al.
BRITISH JOURNAL OF CANCER (2009)
Transcript Level Modulates the Inherent Oncogenicity of RET/PTC Oncoproteins
Douglas S. Richardson et al.
CANCER RESEARCH (2009)
Medullary thyroid carcinoma identified within the first year of life in children with hereditary multiple endocrine neoplasia type 2A (codon 634) and 2B
D. Zenaty et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2009)
Multiple Endocrine Neoplasia Type 2 RET Protooncogene Database: Repository of MEN2-Associated RET Sequence Variation and Reference for Genotype/Phenotype Correlations
Rebecca L. Margraf et al.
HUMAN MUTATION (2009)
Functional RET G691S polymorphism in cutaneous malignant melanoma
N. Narita et al.
ONCOGENE (2009)
RET/PTC rearrangements preferentially occurred in papillary thyroid cancer among atomic bomb survivors exposed to high radiation dose
Kiyohiro Hamatani et al.
CANCER RESEARCH (2008)
Familial prevalence and age of RET germline mutations: implications for screening
Andreas Machens et al.
CLINICAL ENDOCRINOLOGY (2008)
RET oncogene in MEN2, MEN2B, MTC and other forms of thyroid cancer
Maya B. Lodish et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2008)
Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer:: A 10-year follow-up study
Rossella Elisei et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
The relationship between overexpression of glial cell-derived neurotrophic factor and its RET receptor with progression and prognosis of human pancreatic cancer
Q. Zeng et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2008)
GDNF and GFRα:: a versatile molecular complex for developing neurons
Gustavo Paratcha et al.
TRENDS IN NEUROSCIENCES (2008)
Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia
Taranjit S. Gujral et al.
CANCER RESEARCH (2006)
Structure and chemical inhibition of the RET tyrosine kinase domain
Phillip P. Knowles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B
Aaron N. Cranston et al.
CANCER RESEARCH (2006)
The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling
H Sawai et al.
CANCER RESEARCH (2005)
RET tyrosine kinase signaling in development and cancer
E Arighi et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors
F Carlomagno et al.
ONCOGENE (2004)
RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population
R Elisei et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Intronic single nucleotide Polymorphisms in the RET protooncogene are associated with a subset of apparently sporadic pheochromocytoma and may modulate age of onset
SR McWhinney et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Very early detection of RET proto-oncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children -: Presence of C-cell malignant disease in asymptomatic carriers
GE Sanso et al.
CANCER (2002)
Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
E de Graaff et al.
GENES & DEVELOPMENT (2001)
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF
XJ Meng et al.
SCIENCE (2000)
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