期刊
WORLD JOURNAL OF CARDIOLOGY
卷 7, 期 8, 页码 466-475出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4330/wjc.v7.i8.466
关键词
Early repolarization syndrome; Early repolarization; Sudden cardiac death; J-wave
Early repolarization syndrome (ERS), demonstrated as J-point elevation on an electrocardiograph, was formerly thought to be a benign entity, but the recent studies have demonstrated that it can be linked to a considerable risk of life - threatening arrhythmias and sudden cardiac death (SCD). Early repolarization characteristics associated with SCD include high amplitude J-point elevation, horizontal and/or down-slopping ST segments, and inferior and/or lateral leads location. The prevalence of ERS varies between 3% and 24%, depending on age, sex and J-point elevation (0.05 mV vs 0.1 mV) being the main determinants. ERS patients are sporadic and they are at a higher risk of having recurrent cardiac events. Implantable cardioverter-defibrillator implantation and isoproterenol are the suggested therapies in this set of patients. On the other hand, asymptomatic patients with ERS are common and have a better prognosis. The risk stratification in asymptomatic patients with ERS still remains a grey area. This review provides an outline of the up-to-date evidence associated with ERS and the risk of life - threatening arrhythmias. Further prospective studies are required to elucidate the mechanisms of ventricular arrhythmogenesis in patients with ERS. (C) The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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