期刊
EARLY HUMAN DEVELOPMENT
卷 120, 期 -, 页码 75-79出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2018.02.006
关键词
Magnetic resonance imaging; Perinatal asphyxia; Mild neonatal encephalopathy; Hypoxic ischemic encephalopathy; Biomarker
Historically, there has been limited neuro-imaging data acquired on infants with mild neonatal encephalopathy (NE). This likely reflects the traditional assumption that these infants had a universally good prognosis. As new evidence has emerged challenging this assumption, there has been a renewed interest in the neuro-imaging findings of these infants. To date, magnetic resonance imaging (MRI) studies in infants with mild NE have demonstrated abnormalities in 20-40% of cases suggestive that the injury occurs during the peripartum period with a predominant watershed pattern of injury. The severity of the injury on MRI in infants with mild NE varies, but includes patterns of injury that have been associated with long-term neuro-developmental impairment.
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