3.9 Article

MNT Optimization for Intracellular Delivery of Antibody Fragments

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DOKLADY BIOCHEMISTRY AND BIOPHYSICS
卷 479, 期 1, 页码 62-65

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MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1607672918020023

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  1. Russian Science Foundation [17-14-01304]

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We studied the possibility of optimizing modular nanotransporters (MNTs) for the intracellular delivery of antibody fragments into the nuclei of cells of a specified type. Basic MNT with a reduced size retaining the desired functions was obtained, and the principal possibility of obtaining an MNT carrying an antibody fragment by microbiological synthesis was shown.

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