期刊
MATHEMATICAL BIOSCIENCES AND ENGINEERING
卷 12, 期 6, 页码 1141-1156出版社
AMER INST MATHEMATICAL SCIENCES-AIMS
DOI: 10.3934/mbe.2015.12.1141
关键词
Tumor growth; cancer; microenvironment
资金
- Basic Science Research Program through the National Research Foundation of Korea, Ministry of Education and Technology [2012R1A1A1043340]
- NIH [GM29123-36]
- NSF Grants DMS [9517884, 131974]
- National Research Foundation of Korea [2012R1A1A1043340] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Hybrid models of tumor growth, in which some regions are described at the cell level and others at the continuum level, provide a flexible description that allows alterations of cell-level properties and detailed descriptions of the interaction with the tumor environment, yet retain the computational advantages of continuum models where appropriate. We review aspects of the general approach and discuss applications to breast cancer and glioblastoma.
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