期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 48, 期 2, 页码 355-359出版社
IOS PRESS
DOI: 10.3233/JAD-150168
关键词
Dementia; epidemiology; mild cognitive impairment; prevalence
资金
- Innovative Medicines Initiative Joint Undertaking [115372]
- European Union's Seventh Framework Programme (FP7)
- EFPIA
The prevalence of mild cognitive impairment (MCI) and dementia according to age remain uncertain. We systematically extracted age-stratified estimates of MCI and dementia prevalence reported in European studies published since 1995, and performed meta-analyses for dementia. We identified 10 relevant studies on MCI and 26 studies on dementia. Studies on MCI presented substantial heterogeneity preventing a meta-analysis, with a majority reporting an increase in prevalence at >= 75 years old. Pooled prevalence of dementia rose continuously from 55 years of age, reaching 44.7% (39.8; 49.6) in those >= 95 years of age. Homogenization of MCI criteria, and additional studies in Northern European population would be warranted.
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