期刊
DEVELOPMENT
卷 145, 期 13, 页码 -出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/dev.160887
关键词
Target of rapamycin protein kinase; Nutrient signaling; Metabolism reprogramming; Cell cycle regulation; Meristem; Stem cell niche
资金
- National Institute of General Medical Sciences [R01 GM060493, GM070567]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM070567, R01GM060493] Funding Source: NIH RePORTER
Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central role in both plants and animals, despite their distinct developmental programs and survival strategies. Indeed, TOR integrates nutrient, energy, hormone, growth factor and environmental inputs to control proliferation, growth and metabolism in diverse multicellular organisms. Here, we compare the molecular composition, upstream regulators and downstream signaling relays of TOR complexes in plants and animals. We also explore and discuss the pivotal functions of TOR signaling in basic cellular processes, such as translation, cell division and stem/progenitor cell regulation during plant development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据