Fecal Microbiota Transplantation in Patients With Cancer Undergoing Treatment

Fecal microbiota transplantation (FMT) is a technique used to restore the normal body flora to the gut in cases of Clostridium difficile infection (CDI). It involves instillation of the stool of a healthy donor through a nasogastric tube or colonoscopy into the gastrointestinal tract of the patient. More research is needed to determine the parameters of FMT use in patients with cancer. At a Glance CDI is common in patients with cancer because of the frequent use of broad-spectrum antibiotics that can alter the normal microbiota in the gastrointestinal tract. CDI reoccurs frequently and can be difficult to treat. CDI can delay continued treatment, prolong hospitalizations, and greatly affect a patient's quality of life.