期刊
FORENSIC SCIENCE INTERNATIONAL-GENETICS
卷 19, 期 -, 页码 130-133出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.fsigen.2015.07.006
关键词
PowerPlex (R) Y23; Y-chromosome; Haplotypes; Population data; Forensics
资金
- Five-twelfth' National Science and Technology Support Program of China [2012BAK16B01]
- National Natural Science Foundation of China [81273349, 81330073]
Genetic analysis of Y-STRs has the potential to be used to explore the complexity in population substructures and to perform forensic ancestry inference. In this study, 334 individuals from 12 populations were typed using the PowerPlex (R) Y23 System (Promega, USA) to investigate their relationship. Population comparisons with other East Asian populations collated from YHRD (Y-STR Haplotype Reference Database) were also performed. Variant alleles, including seven intermediate alleles in 15 samples were observed, while the novel allele 11.3 at the DYS549 locus was confirmed by sequencing. Our results showed that the fraction of unique haplotypes differed among the 12 populations studied here. A close relationship was found between Chinese and other East Asian populations. The present study contributed to the enrichment of the forensic Y-chromosome databases with a high resolution 23 Y-STR marker set, which is informative in forensic casework, such as familial searching and estimating the geographical origin of the offender. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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