期刊
CURRENT ANALYTICAL CHEMISTRY
卷 15, 期 2, 页码 166-171出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573411014666180313115001
关键词
Epinephrine; tyrosine; ZnO-Pt/CNTs nanocomposite; electrochemical sensors; carbon electrode; biological compounds
资金
- University of Bahonar
- Quchan University of Technology
Background: Simultaneous analysis of epinephrine and tyrosine as two effective and important biological compounds in human blood and urine samples are very important for the investigation of human health. Objective: In this research, a highly effective voltammetric sensor fabricated for simultaneous analysis of epinephrine and tyrosine. The sensor was fabricated by the modification of glassy carbon electrode with ZnO-Pt/CNTs nanocomposite (ZnO-Pt/CNTs/GCE). The synthesized nanocomposite was characterized by SEM method. The ZnO-Pt/CNTs/GCE showed two separated oxidation signals at potential similar to 220 mV and 700 mV for epinephrine and tyrosine, respectively. Also, we detected linear dynamic ranges 0.5-250.0 mu M and 1.0-220 mu M with a limit of detections 0.1 mu M and 0.5 mu M for the determination of epinephrine and tyrosine, respectively. The ZnO-Pt/CNTs/GCE was used for the determination of epinephrine and tyrosine in blood serum and human urine samples.
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