期刊
ANTIOXIDANTS
卷 4, 期 4, 页码 750-767出版社
MDPI
DOI: 10.3390/antiox4040750
关键词
curcumin monoglucuronide; Anti-oxidant; curcumin diglucuronide; DPPH; Synthesis; ORAC
资金
- Sami Labs Limited, Bangalore, India
- Department of Science and Technology (DST), New Delhi, India
Curcumin metabolites namely curcumin monoglucuronide and curcumin diglucuronide were synthesized using an alternative synthetic approach. The anti-oxidant potential of these curcumin glucuronides was compared with that of curcumin using DPPH scavenging method and Oxygen Radical Absorbance Capacity (ORAC) assay. The results show that curcumin monoglucuronide exhibits 10 fold less anti-oxidant activity (DPPH method) and the anti-oxidant capacity of curcumin diglucuronide is highly attenuated compared to the anti-oxidant activity of curcumin.
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