4.5 Article

The microbiome quality control project: baseline study design and future directions

期刊

GENOME BIOLOGY
卷 16, 期 -, 页码 -

出版社

BMC
DOI: 10.1186/s13059-015-0841-8

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资金

  1. Intramural Research Program of the National Cancer Institute
  2. NIH Common Fund [U01 HG004866]
  3. Sloan Microbiology of the Built Environment program
  4. Cohn's and Colitis Foundation of America
  5. NSF CAREER grant [DBI-1053486]
  6. NIH [U54DE023798]
  7. Crohn's and Colitis Foundation of America [6109799-01]
  8. Direct For Biological Sciences
  9. Div Of Biological Infrastructure [1053486] Funding Source: National Science Foundation

向作者/读者索取更多资源

Microbiome research has grown exponentially over the past several years, but studies have been difficult to reproduce across investigations. Relevant variation in measurements between laboratories, from a variety of sources, has not been systematically assessed. This is coupled with a growing concern in the scientific community about the lack of reproducibility in biomedical research. The Microbiome Quality Control project (MBQC) was initiated to identify sources of variation in microbiome studies, to quantify their magnitudes, and to assess the design and utility of different positive and negative control strategies. Here we report on the first MBQC baseline study project and workshop.

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