期刊
CLINICAL NURSING RESEARCH
卷 29, 期 2, 页码 73-83出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1054773818757312
关键词
depressive symptoms; heart failure; symptoms; symptoms profile
类别
资金
- National Institutes of Health/National Institutes of Nursing Research National Research Service Award [5F32 NR010451-02]
- Interdisciplinary Pilot Research Grant National Institutes of Health/National Institute of Nursing Research [P20 NR007798]
- National Center for Advancing Translational Sciences of the National Institutes of Health [UL1TR00045]
- Biosite, Inc.
- American Heart Association [10SDG3720048]
Heart failure (HF) symptoms are known to influence depressive symptoms, yet a symptom profile has not been identified. HF symptoms relative to symptom experience (frequency, severity, interference with physical activity and enjoyment of life) associated with depressive symptoms were examined. Data from three HF studies (N = 308) which used the Heart Failure Symptom Survey were included in this cross-sectional secondary analysis. Supervised classification for and identification of symptoms most associated with depressive symptoms were accomplished using random forest algorithms via conditional inference trees. The HF symptom profile associated with depressive symptoms across all four symptom experience domains included fatigue, dizziness, and forgetfulness/difficulty concentrating. Abdominal bloating, worsening cough, and difficulty sleeping were also important, but did not consistently rank in the top 5 for symptom importance relative to all symptom experience domains. Symptom profiling may enhance early identification of patients at risk for depressive symptoms and inform symptom management interventions.
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