期刊
CLINICAL BREAST CANCER
卷 18, 期 5, 页码 E985-E995出版社
CIG MEDIA GROUP, LP
DOI: 10.1016/j.clbc.2018.06.003
关键词
Accuracy; Breast cancer; Contrast-enhanced spectral mammography; Meta-analysis
类别
资金
- Guangxi Colleges and Universities Science and Technology Research Projects [KY2015LX054]
- Postgraduate Course Construction of Guangxi Medical University Project [YJSB2017013]
- Innovation Project of Guangxi Graduate Education [YCBZ2017041]
- Humanities Base Project of Guangxi Medical University [2016RWB04]
- International Communication of Guangxi Medical University Graduate Education Project
A new meta-analysis review is needed to evaluate the diagnostic value of contrast-enhanced spectral mammography (CESM). Eighteen studies were included in the review. The important parameters of CESM accuracy for breast cancer diagnosis were analyzed. CESM can be considered as a useful triage test for initial assessment of breast lesions. Background: Contrast-enhanced spectral mammography (CESM) is a new image examination technology that has developed over the past few years. As CESM technology keeps improving, a current meta-analysis review is needed to systematically evaluate the potential diagnostic value of CESM. Methods: A total of 18 studies were included in the review. Sensitivity, specificity, and other important parameters of CESM accuracy for breast cancer diagnosis were pooled and analyzed using random-effects models. Summary receiver operating characteristic curves were calculated for overall accuracy estimation. Results: The summary estimates for CESM in the diagnosis of breast cancer were as follows: the pooled sensitivity and specificity were 0.89 (95% confidence interval [CI], 0.88-0.91) and 0.84 (95% CI, 0.82-0.85), respectively. Positive likelihood ratio was 3.73 (95% CI, 2.68-5.20), negative likelihood ratio was 0.10 (95% CI, 0.06-0.15), and diagnostic odds ratio was 71.36 (95% CI, 36.28-140.39). The area under the curve was 0.96 (standard error = 0.011). Conclusion: CESM has a high diagnostic accuracy for evaluating breast cancer and can be considered as a useful test for initial assessment of breast lesions. (C) 2018 Elsevier Inc. All rights reserved.
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