期刊
MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION, PT III
卷 9351, 期 -, 页码 242-250出版社
SPRINGER INT PUBLISHING AG
DOI: 10.1007/978-3-319-24574-4_29
关键词
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We propose a novel microscopy image restoration algorithm capable of co-restoring Phase Contrast and Differential Interference Contrast (DIC) microscopy images captured on the same cell dish simultaneously. Cells with different phase retardation and DIC gradient signals are restored into a single image without the halo artifact from phase contrast or pseudo 3D shadow-casting effect from DIC. The co-restoration integrates the advantages of two imaging modalities and overcomes the drawbacks in single-modal image restoration. Evaluated on a datasets of five hundred pairs of phase contrast and DIC images, the co-restoration demonstrates its effectiveness to greatly facilitate the cell image analysis tasks such as cell segmentation and classification.
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