期刊
CIRCULATION RESEARCH
卷 123, 期 3, 页码 332-334出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCRESAHA.118.313406
关键词
atrial fibrillation; cell lines; gene targeting; mice; oocytes
资金
- German Research Foundation DFG [Do 769/4-1]
- National Institutes of Health (NIH) [R01-HL131517, R01-HL136389]
- NIH [R01-HL089598, R01-HL091947, R01-HL117641, R01-HL134824]
Mouse models have been invaluable for delineating the contributions of specific genes and signaling pathways to the pathogenesis of cardiac arrhythmias. Considering that there are important differences between mice and humans, here we discuss the strengths and limitations of mouse models of cardiac arrhythmias.
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