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MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
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JOURNAL OF EXPERIMENTAL MEDICINE (2009)
PCNA Is Required for Initiation of Recombination-Associated DNA Synthesis by DNA Polymerase δ
Xuan Li et al.
MOLECULAR CELL (2009)
Counting RAD51 proteins disassembling from nucleoprotein filaments under tension
Joost van Mameren et al.
NATURE (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Complex landscapes of somatic rearrangement in human breast cancer genomes
Philip J. Stephens et al.
NATURE (2009)
Multiple functions of MRN in end-joining pathways during isotype class switching
Maria Dinkelmann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
Anyong Xie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
Emilie Rass et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules
Amitabh V. Nimonkar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs
Shunichi Kosugi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
Shirley M. H. Sy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination
Louise J. Barber et al.
CELL (2008)
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
Zhu Zhu et al.
CELL (2008)
Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination
Jesus A. Carballo et al.
CELL (2008)
Break-induced replication - What is it and what is it for?
Bertrand Llorente et al.
CELL CYCLE (2008)
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
Serge Gravel et al.
GENES & DEVELOPMENT (2008)
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis
Anuradha Sourirajan et al.
GENES & DEVELOPMENT (2008)
BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome
Thiyam Ramsing Singh et al.
GENES & DEVELOPMENT (2008)
A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae
K. T. Nishant et al.
GENETICS (2008)
RECQ1 possesses DNA branch migration activity
Dmitry V. Bugreev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair
Michael J. Mcllwraith et al.
MOLECULAR CELL (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas et al.
NATURE (2008)
Identification of Holliday junction resolvases from humans and yeast
Stephen C. Y. Ip et al.
NATURE (2008)
Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis
Miki Shinohara et al.
NATURE GENETICS (2008)
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
Kirk Tevebaugh Ehmsen et al.
NUCLEIC ACIDS RESEARCH (2008)
Remodeling of DNA replication structures by the branch point translocase FANCM
Kerstin Gari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
Nicole Bennardo et al.
PLOS GENETICS (2008)
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
Yiduo Hu et al.
GENES & DEVELOPMENT (2007)
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
Dmitry V. Bugreev et al.
GENES & DEVELOPMENT (2007)
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
Bettina M. Lengsfeld et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair
Carol E. Schrader et al.
JOURNAL OF IMMUNOLOGY (2007)
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
Angelo Lombardo et al.
NATURE BIOTECHNOLOGY (2007)
Rad54 dissociates homologous recombination intermediates by branch migration
Dmitry V. Bugreev et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing
Roberto J. Pezza et al.
GENES & DEVELOPMENT (2007)
Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase
Peter Chi et al.
GENES & DEVELOPMENT (2007)
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
Yu Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2
Mark I. R. Petalcorin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
ZMM proteins during meiosis: Crossover artists at work
Audrey Lynn et al.
CHROMOSOME RESEARCH (2007)
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
Minli Wang et al.
NUCLEIC ACIDS RESEARCH (2006)
Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
Radhakrishnan Kanagaraj et al.
NUCLEIC ACIDS RESEARCH (2006)
Topoisomerase IIIα and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migration
Jody L. Plank et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Sws1 is a conserved regulator of homologous recombination in eukaryotic cells
Victoria Martin et al.
EMBO JOURNAL (2006)
Dual roles for DNA polymerase η in homologous DNA recombination and translesion DNA synthesis
T Kawamoto et al.
MOLECULAR CELL (2005)
Human DNA polymerase η promotes DNA synthesis from strand invasion intermediates of homologous recombination
MJ McIlwraith et al.
MOLECULAR CELL (2005)
Partner choice during meiosis is regulated by Hop1-promoted dimerization of Mek1
HY Niu et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
MJ Neale et al.
NATURE (2005)
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
CE Schrader et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions
M Yabuki et al.
NATURE IMMUNOLOGY (2005)
The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination
GV Petukhova et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
JH Lee et al.
SCIENCE (2005)
ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombinational repair of a DNA double strand break
B Wolner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
HJ Yang et al.
NATURE (2005)
Early decision: Meiotic crossover interference prior to stable strand exchange and synapsis
DK Bishop et al.
CELL (2004)
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
JH Lee et al.
SCIENCE (2004)
Saccharomyces cerevisiae MER3 helicase stimulates 3′-5′ Heteroduplex extension by Rad51:: Implications for crossover control in meiotic recombination
OM Mazina et al.
CELL (2004)
Association of Mre11p with double-strand break sites during yeast meiosis
V Borde et al.
MOLECULAR CELL (2004)
hMSH4-hMSH5 recognizes Holliday junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes
T Snowden et al.
MOLECULAR CELL (2004)
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
M Audebert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
G Ira et al.
NATURE (2004)
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
L Wu et al.
NATURE (2003)
The Mre11 complex is required for ATM activation and the G2/M checkpoint
CT Carson et al.
EMBO JOURNAL (2003)
Requirement of the MRN complex for ATM activation by DNA damage
T Uziel et al.
EMBO JOURNAL (2003)
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
K Imai et al.
NATURE IMMUNOLOGY (2003)
The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism
PHL Gaillard et al.
MOLECULAR CELL (2003)
Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3
WM Fricke et al.
GENES & DEVELOPMENT (2003)
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
P Pham et al.
NATURE (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation
H Zan et al.
IMMUNITY (2003)
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
X Veaute et al.
NATURE (2003)
DNA helicase Srs2 disrupts the Rad51 presynaptic filament
L Krejci et al.
NATURE (2003)
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
KC Wei et al.
GENES & DEVELOPMENT (2003)
Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers
Ö Yildiz et al.
MOLECULAR CELL (2002)
Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae
PT Tran et al.
DNA REPAIR (2002)
Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments
JA Solinger et al.
MOLECULAR CELL (2002)
The Rad51-dependent pairing of long DNA substrates is stabilized by replication protein A
AL Eggler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
C Rada et al.
CURRENT BIOLOGY (2002)
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
HJ Yang et al.
SCIENCE (2002)
Meiotic arrest and aneuploidy in MLH3-deficient mice
SM Lipkin et al.
NATURE GENETICS (2002)
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
JM Sogo et al.
SCIENCE (2002)
AID mutates E-coli suggesting a DNA deamination mechanism for antibody diversification
SK Petersen-Mahrt et al.
NATURE (2002)
Close, stable homolog juxtaposition during meiosis in budding yeast is dependent on meiotic recombination, occurs independently of synapsis, and is distinct from DSB-independent pairing contacts
TL Peoples et al.
GENES & DEVELOPMENT (2002)
Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining
C Chappell et al.
EMBO JOURNAL (2002)
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
YM Ma et al.
CELL (2002)
Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion
H Arakawa et al.
SCIENCE (2002)
Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction
JR Huang et al.
NUCLEIC ACIDS RESEARCH (2002)
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange
S Sigurdsson et al.
GENES & DEVELOPMENT (2001)
Identification and purification of two distinct complexes containing the five RAD51 paralogs
JY Masson et al.
GENES & DEVELOPMENT (2001)
Mus81-Eme1 are essential components of a Holliday junction resolvase
MN Boddy et al.
CELL (2001)
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdfl/Hdf2 complexes
L Chen et al.
MOLECULAR CELL (2001)
The DNA replication checkpoint response stabilizes stalled replication forks
M Lopes et al.
NATURE (2001)
Rescue of stalled replication forks by RecG: Simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation
P McGlynn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Differential timing and control of noncrossover and crossover recombination during meiosis
T Allers et al.
CELL (2001)
The single-end invasion: An asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination
N Hunter et al.
CELL (2001)
Recombinational DNA double-strand breaks in mice precede synapsis
SK Mahadevaiah et al.
NATURE GENETICS (2001)
Cell-cycle-regulated DNA double-strand breaks in somatic hypermutation of immunoglobulin genes
FN Papavasiliou et al.
NATURE (2000)
Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11
F Baudat et al.
MOLECULAR CELL (2000)
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity
RM Brosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in DNA strand exchange
BW Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
M Muramatsu et al.
CELL (2000)
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