期刊
FOOD AND CHEMICAL TOXICOLOGY
卷 86, 期 -, 页码 274-281出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2015.10.017
关键词
Cumulative risk assessment; Children; Multiple mycotoxins; Breakfast cereals; Probabilistic analysis
资金
- Fundacao para a Ciencia e Tecnologia (FCT), Portugal [CESAM: UID/AMB/50017/2013, PTDC/DTP-FTO/0417/2012]
- Fundação para a Ciência e a Tecnologia [PTDC/DTP-FTO/0417/2012] Funding Source: FCT
Humans can be exposed to multiple chemicals, but current risk assessment is usually carried out on one chemical at a time. Mycotoxins are commonly found in a variety of foods including those intended to consumption by children namely breakfast cereals. The present study aims to perform, the risk assessment of single and multiple mycotoxins present in breakfast cereals consumed by children (1-3 years old) from Lisbon region, Portugal. Daily exposure of children to ochratoxin A, fumonisins and trichothecenes showed no health risks to the children population considering individual mycotoxins, while exposure to aflatoxin B-1 (AFB(1)) suggested a potential health concern for the high percentiles of intake (P90, P95 and P99). The combined exposure to fumonisins and trichothecenes are not expected to be of health concern. The combined margin of exposure (MoET) for the aflatoxins group could constitute a potential health concern and AFB(1) was the main contributor for MoET. Legal limits and control strategies regarding the presence of multiple mycotoxins in foodstuffs is an urgent need. To the best of our knowledge, this is the first time a cumulative risk assessment was performed on multiple mycotoxins present in breakfast cereals consumed by children. (C) 2015 Elsevier Ltd. All rights reserved.
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