期刊
FOOD AND CHEMICAL TOXICOLOGY
卷 86, 期 -, 页码 16-24出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2015.09.011
关键词
Antioxidant activity; Antiproliferative activity; Flavonoid content; Terpene and sterol composition
Thirteen bydroalcoholic extracts of edible plants from Southern Italy were evaluated for their in vitro antioxidant and antiproliferative activity on three human cancer cell lines: breast cancer MCF-7, hepatic cancer HepG2 and colorectal cancer LoVo. After 48 h of incubation the most antiproliferative plant extract was rosemary (Rosmarinus officinalis L.) on LoVo cell line with IC50 of 16.60 mu g/ml. Oregano (Origanum vulgare L. subsp. viridulum) showed a selective antiproliferative activity on hepatic cancer with IC50 of 32.59 mu g/ml. All the extracts, with the exception of Diplotaxis tenuifolia (L.) DC., exerted antioxidant properties, the most active plants being dewberry (Rubus caesius L.) and Iaprista (Rumex conglomerates Murray) with IC50 of 4.91 and 5.53 mu g/ml, respectively. Rumex conglomeratus contained the highest amount of flavonoids (15.5- mg/g) followed by Portulaca oleracea L (11.8 mg/g). Rosmarinus officinalis contained the highest number of terpenes. Among them ketoursene (14.7%) and aristolorie (11.3%) were found to be the major constituents. P. oleracea and Raphanus raphanistrum L. subsp. landra contained the highest number of sterols. (C) 2015 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据