4.1 Article

Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy

期刊

CLINICAL CASE REPORTS
卷 3, 期 6, 页码 379-387

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WILEY
DOI: 10.1002/ccr3.238

关键词

Chloroquine; chronic effects; CYP2D6; genetic polymorphisms; pharmacogenetics; psychosis; quinoline

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Susceptibility to quinoline antimalarial intoxication may reflect individual genetic and drug-induced variation in neuropharmacokinetics. In this report, we describe a case of chloroquine intoxication that appeared to be prolonged by subsequent use of multiple psychotropic medications. This case highlights important new considerations for the management of quinoline antimalarial intoxication.

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