期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 24, 期 49, 页码 12938-12949出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201801803
关键词
antibacterial; bismuth; materials; nanocellulose; phosphinate
资金
- Monash University
- Australian Research Council [DP 170103624]
A series of poorly soluble phenyl bis-phosphinato bismuth(III) complexes [BiPh(OP(=O)(RR2)-R-1)(2)] (R-1=R-2=Ph; R-1=R-2=p-OMePh; R-1=R-2=m-NO2Ph; R-1=Ph, R-2=H; R-1=R-2=Me) have been synthesised and characterised, and shown to have effective antibacterial activity against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). The bismuth complexes were incorporated into microfibrillated (nano-) cellulose generating a bismuth-cellulose composite as paper sheets. Antibacterial evaluation indicates that the Bi-cellulose materials have analogous or greater activity against Gram positive bacteria when compared with commercial silver based additives: silver sulfadiazine loaded at 0.43 wt% into nanocellulose produces a 10 mm zone of inhibition on the surface of agar plates containing S. aureus whereas [BiPh(OP(=O)Ph-2)(2)] loaded at 0.34 wt% produces an 18 mm zone of inhibition. These phenyl bis-phosphinato bismuth(III) complexes show potential to be applied in materials in healthcare facilities, to inhibit the growth of bacteria capable of causing serious disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据