期刊
CHEMISTRY OF NATURAL COMPOUNDS
卷 54, 期 3, 页码 520-522出版社
SPRINGER
DOI: 10.1007/s10600-018-2394-z
关键词
L-alanine derivative; antifungal activity; mangrove endophytic fungus; Penicillium sp.
资金
- National Natural Science Foundation of China [21102049]
- Natural Science Foundation of Guangdong Province of China [2015A030313405, 9451064201003751]
- Science and Technology Project for public welfare research and capacity building of Guangdong Province [2016A020222019]
- Science and Technology Project of Guangzhou City [201605112013464, 11C12100771]
- Scientific Research Foundation for the Returning Overseas Chinese Scholars, State Education Ministry [2015-311]
A new L-alanine derivative, N-fumaryl-L-alanine dimethyl ester (1), and a new natural product N,N-bis[(S)-1-methoxycarbonylethyl]fumaric diamide (2), along with three known compounds sohirnone A (3), chaetoglobosin C (4), and chaetoglobosin F (5), were isolated from the mangrove endophytic fungus Penicillium chrysogenum V11. Their structures were elucidated by comprehensive spectroscopic analyses. Primary bioassays showed that compounds 3, 4, and 5 had moderate or weak in vitro antifungal activities on Fusarium oxysporum and/or Rhizoctonia solani.
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