期刊
CHEMISTRY AND ECOLOGY
卷 34, 期 5, 页码 397-411出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/02757540.2018.1437148
关键词
Chemical ecology; sponge; competition
资金
- Continuous Operational and Outcomes-based Partnership in Research and Academic Training Enhancement (COOPERATE) [915-229]
- Emerging Interdisciplinary Research (EIDR) - Social ecological resilience on different spatial and temporal scales (emphasis on the coast) [1-005-121113]
Marine sponges can produce allelopathic compounds with specific roles in the competition for benthic space. Here we demonstrate that extracts from Callyspongia samarensis (Phylum Porifera) accelerate bleaching in Porites cylindrica (Phylum Cnidaria, Order Scleractinia) and exhibit in vitro anticancer activity. A column chromatography fraction and HPLC fraction, purified from the crude methanol extract of C. samarensis, were incorporated into agar gel cubes at natural concentrations and tested on P. cylindrica corals in a laboratory assay. Statistical analysis of percent bleached area and maximum quantum yield showed that a significant difference existed between P. cylindrica nubbins that were exposed to C. samarensis extracts versus the control group. This suggests that C. samarensis contains allelopathic compounds that can cause bleaching in P. cylindrica, possibly leading to tissue necrosis and death. Furthermore, the aforementioned HPLC fraction exhibited significant growth inhibition of the HCT-116 (human colon cancer) cell line. Understanding the strategies by which sponges exert dominance over other organisms is important because it provides information about the ecological roles of sponge allelopathy and can result in the discovery of compounds with biomedical potential.
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