期刊
CHEMICAL SOCIETY REVIEWS
卷 47, 期 15, 页码 5946-5996出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cs00825a
关键词
-
资金
- NRF Basic Research Laboratory Program [2016R1A4A1011451]
- NRF Nano Material Technology Development Program [2012M3A7B4049652]
- National Research Foundation of Korea [2012M3A7B4049645, 2016R1A4A1011451, 2012M3A7B4049652] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The enantioselective synthesis of spirocycles has long been pursued by organic chemists. Despite their unique 3D properties and presence in several natural products, the difficulty in their enantioselective synthesis makes them underrepresented in pharmaceutical libraries. Since the first pioneering reports of the enantioselective construction of spirosilanes by Tamao et al., significant effort has been devoted towards the development of new promising asymmetric methodologies. Remarkably, with the advent of organocatalysis, particularly over six years, the reported methodologies for the synthesis of spirocycles have increased exponentially. The aim of this review is to summarize the latest trends and developments in the enantioselective synthesis of spirocompounds during these last six years.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据