期刊
CHEMICAL SOCIETY REVIEWS
卷 47, 期 12, 页码 4295-4313出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cs00914c
关键词
-
资金
- National Natural Science Foundation of China [21621004, 21776213, 91534126, 21406163]
- Tianjin Research Program of Application Foundation and Advanced Technology [15JCQNJC10000]
- Open Funding Project of the National Key Laboratory of Biochemical Engineering [2015KF-03]
- Program of Introducing Talents of Discipline to Universities [B06006]
Enzyme catalysis, as a green, efficient process, displays exceptional functionality, adaptivity and sustainability. Multi-enzyme catalysis, which can accomplish the tandem synthesis of valuable materials/chemicals from renewable feedstocks, establishes a bridge between single-enzyme catalysis and whole-cell catalysis. Multi-enzyme catalysis occupies a unique and indispensable position in the realm of biological reactions for energy and environmental applications. Two complementary strategies, i.e., compartmentalization and substrate channeling, have been evolved by living organisms for implementing the complex in vivo multi-enzyme reactions (MERs), which have been applied to construct multi-enzyme catalytic systems (MECSs) with superior catalytic activity and stabilities in practical biocatalysis. This tutorial review aims to present the recent advances and future prospects in this burgeoning research area, stressing the features and applications of the two strategies for constructing MECSs and implementing in vitro MERs. The concluding remarks are presented with a perspective on the construction of MECSs through rational combination of compartmentalization and substrate channeling.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据