期刊
CHEMICAL SOCIETY REVIEWS
卷 47, 期 15, 页码 5646-5683出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cs00263g
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资金
- National Natural Science Foundation of China [21474060, 21574078, 21327902]
- Shanghai Rising-Star Program [16QA1401800]
- China Scholarship Council [201606895013, 201606210262]
- National Key R&D Program of China [2016YFA0201200]
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [NRF-2018R1D1A1B07041102]
- POSTECH Basic Science Research Institute
- National Science Foundation [DMR-1708729, DMR-1420570]
- National Institutes of Health [P01GM096971, R01EB023287]
- National Research Foundation of Korea [2017R1C1B2006237] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale, enabling fabrication of advanced microparticles with precisely tunable structures and compositions in a high throughput manner. The combination of these remarkable features with proper materials and fabrication methods has enabled high efficiency, direct encapsulation of actives in microparticles whose features and functionalities can be well controlled. These microparticles have great potential in a wide range of bio-related applications including drug delivery, cell-laden matrices, biosensors and even as artificial cells. In this review, we briefly summarize the materials, fabrication methods, and microparticle structures produced with droplet microfluidics. We also provide a comprehensive overview of their recent uses in biomedical applications. Finally, we discuss the existing challenges and perspectives to promote the future development of these engineered microparticles.
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