Pd-Catalyzed reductive heck reaction of olefins with aryl bromides for Csp(2)-Csp(3) bond formation

We developed a Pd-catalyzed intermolecular reductive Heck reaction to construct Csp(2)-Csp(3) bonds between aryl bromides and olefins. Various styrene derivatives, acyclic and cyclic alkenes, were well tolerated to couple with varied aryl bromides in linear selectivity. Kinetic and deuterium labeling experiments suggested that i-PrOH provides a hydride through -H elimination.