Electrochemical dehydrogenative cyclization of 1,3-dicarbonyl compounds

The intramolecular C(sp(3))-H/C(sp(2))-H cross-coupling of 1,3-dicarbonyl compounds has been achieved through Cp2Fe-catalyzed electrochemical oxidation. The key to the success of these dehydrogenative cyclization reactions is the selective activation of the acidic -C-H bond of the 1,3-dicarbonyl moiety to generate a carbon-centered radical.