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Ultrasensitive electrochemical immunoassay for melanoma cells using mesoporous polyaniline

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CHEMICAL COMMUNICATIONS
卷 54, 期 7, 页码 710-714

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc09248b

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  1. National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health (NIH) [P30 AR066524]
  2. Skin Diseases Research Center at the University of Wisconsin
  3. University of Wisconsin Carbone Cancer Center Support Grant [P30 CA014520]
  4. NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [P30AR066524] Funding Source: NIH RePORTER

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We report the development of an antibody (anti-MC1R antibody)-functionalized polyaniline nanofibers modified screen-printed electrode capable of efficient electrochemical detection of melanoma cells at levels (1 cell per mL) not readily achieved by other methods. This immunosensor is highly selective in its detection of melanoma cells over normal human cells.

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