期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 5, 页码 449-451出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc08300a
关键词
-
资金
- DFG [RE2796/6-1, EXC 1003]
- Fonds der Chemischen Industrie
- Fonds der Chemischen Industrie (Dozentenpreis)
Methyltransferases are powerful tools for site-specific transfer of non-natural functional groups from synthetic analogs of their cosubstrate S-adenosyl-L-methionine (AdoMet). We present a new class of AdoMet analogs containing photo-caging (PC) groups in their side chain, enzymatic transfer of PC groups by a promiscuous DNA MTase as well as light-triggered removal from the target DNA. This strategy provides a new avenue to reversibly modulate the functionality of DNA at MTase target sites.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据