期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 14, 页码 1710-1713出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc08427g
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-
资金
- National Sciences Foundation of China [21402189, 21572222]
- Innovative Team of Sichuan Province [2017TD0021]
A novel colorimetric method which utilizes DNAzyme as a signal reporter was developed for DNA methylation detection. As low as 1/10(6) of methylated DNA could be successfully detected from unmethylated DNA. The discrimination ability is at least two orders of magnitude better than that of the methylation specific PCR.
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