相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。NMR studies of the non-haem Fe(II) and 2-oxoglutarate-dependent oxygenases
Naasson M. Mbenza et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2017)
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
Tzu-Lan Yeh et al.
CHEMICAL SCIENCE (2017)
Targeting Protein-Protein Interactions in the HIF System
Sarah E. Wilkins et al.
CHEMMEDCHEM (2016)
Pharmacological targeting of the HIF hydroxylases - A new field in medicine development
Mun Chiang Chan et al.
MOLECULAR ASPECTS OF MEDICINE (2016)
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
Rasheduzzaman Chowdhury et al.
NATURE COMMUNICATIONS (2016)
Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel-Lindau Suppressor
Carmen Domene et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
Mun Chiang Chan et al.
PLOS ONE (2015)
Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen
Hanna Tarhonskaya et al.
BIOCHEMICAL JOURNAL (2014)
Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours
Cameron E. Snell et al.
PLOS ONE (2014)
Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy
Ovidiu C. Andronesi et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
Christoph Loenarz et al.
EMBO REPORTS (2011)
Chemical Basis for the Selectivity of the von Hippel Lindau Tumor Suppressor pVHL for Prolyl-Hydroxylated HIF-1α
Christopher J. R. Illingworth et al.
BIOCHEMISTRY (2010)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (vol 462, pg 739, 2010)
Lenny Dang et al.
NATURE (2010)
Use of mass spectrometry to probe the nucleophilicity of cysteinyl residues of prolyl hydroxylase domain 2
Jasmin Mecinovic et al.
ANALYTICAL BIOCHEMISTRY (2009)
Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases
Rasheduzzaman Chowdhury et al.
STRUCTURE (2009)
ESI-MS studies on prolyl hydroxylase domain 2 reveal a new metal binding site
Jasmin Mecinovic et al.
CHEMMEDCHEM (2008)
Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases
Emily Flashman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates
Kirsty S. Hewitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cellular oxygen sensing:: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)
Michael A. McDonough et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Signalling hypoxia by HIF hydroxylases
CJ Schofield et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate
LA McNeill et al.
MOLECULAR BIOSYSTEMS (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
RJ Appelhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Congenital disorder of oxygen sensing:: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
VR Gordeuk et al.
BLOOD (2004)
Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Structural basis for the recognition of hydroxyproline in αIF-1α by pVHL
WC Hon et al.
NATURE (2002)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)