Fabrication of a novel ZnO-CoO/rGO nanocomposite for nonenzymatic detection of glucose and hydrogen peroxide

Herein, a novel nanocomposite of binary ZnO-CoO nanoparticles loaded on the graphene nanosheets (ZnO-CoO/rGO) has been successfully constructed via a facile, economical and two-step process. The obtained ZnO-CoO/rGO hybrids with high electrical conductivity and abundant active sites, could be modified on a glassy carbon electrode to detect glucose and H2O2 multi-functionally. The fabricated biosensor exhibits wide linear range for glucose (10 mu M to 11.205 mM) and H2O2 (25 mu M to 11.1 mM), and their corresponding sensitivity are 168.7 mu A mM(-1) cm(-2) and 183.3 mu A mM(-1) cm(-2). The limits of detection are 1.3 mu M and 0.44 mu M for the oxidation of glucose and the reduction of H2O2, respectively. Furthermore, remarkable selectivity, long-term stability and outstanding reproducibility of the non-enzyme biosensor prove that ZnO-CoO/rGO hybrids are the promising candidate in practical applications.