期刊
FITOTERAPIA
卷 105, 期 -, 页码 156-159出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2015.07.002
关键词
Acronychia oligophlebia; Prenylated acetophenone; Cytotoxic activity
资金
- National Natural Science Foundation of China [81202429, 81273390, 81473116]
- Natural Science Foundation of Guangdong Province [S2013020012864]
- 111 Project [B13038]
Six new prenylated acetophenone derivatives were isolated from the leaves of Acronychia oligophlebia. The chemical structures of them were elucidated by extensive analysis of spectroscopic data (IR, UV, HRESIMS, 1D and 2D NMR). The cytotoxic activity of the isolates was evaluated against MCF-7 cells. Among these compounds, 2 and 6 exhibited mild cytotoxic activity with IC50 values of 33.5 and 25.6 mu M, respectively. (C) 2015 Elsevier B.V. All rights reserved.
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