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CANCER RESEARCH (2016)
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer
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NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells
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CANCER MEDICINE (2016)
NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea
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Nrf2 Expressions Correlate with WHO Grades in Gliomas and Meningiomas
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Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer
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HUMAN PATHOLOGY (2015)
NRF2 regulates serine biosynthesis in non-small cell lung cancer
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NATURE GENETICS (2015)
Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer
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HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2015)
Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients
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NEURO-ONCOLOGY (2015)
Functional Role of NRF2 in Cervical Carcinogenesis
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PLOS ONE (2015)
Nrf2 is Useful for Predicting the Effect of Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma
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ANNALS OF SURGICAL ONCOLOGY (2014)
Myeloid Lineage-Specific Deletion of Antioxidant System Enhances Tumor Metastasis
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CANCER PREVENTION RESEARCH (2014)
Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
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CANCER RESEARCH (2014)
NRF2 immunolocalization in human breast cancer patients as a prognostic factor
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Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers
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MOLECULAR AND CELLULAR BIOLOGY (2014)
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MOLECULAR AND CELLULAR BIOLOGY (2014)
Nuclear Nrf2 expression is related to a poor survival in pancreatic adenocarcinoma
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PATHOLOGY RESEARCH AND PRACTICE (2014)
The Nrf2 transcription factor contributes to resistance to cisplatin in bladder cancer
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Nrf2 Overexpression Predicts Prognosis and 5-FU Resistance in Gastric Cancer
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ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2013)
Nrf2 is required to maintain the self-renewal of glioma stem cells
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BMC CANCER (2013)
Nrf2 Prevents Initiation but Accelerates Progression through the Kras Signaling Pathway during Lung Carcinogenesis
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CANCER RESEARCH (2013)
Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels
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MOLECULAR AND CELLULAR BIOLOGY (2013)
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
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MOLECULAR CELL (2013)
Mutational landscape and significance across 12 major cancer types
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NATURE (2013)
Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
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Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model
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Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
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CANCER CELL (2012)
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SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
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MOLECULAR AND CELLULAR BIOLOGY (2011)
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
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CLINICAL CANCER RESEARCH (2010)
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MOLECULAR AND CELLULAR BIOLOGY (2010)
Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth
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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Different electrostatic Potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
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Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis
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CANCER RESEARCH (2004)
Nrf2-Keap1 defines a physiologically important stress response mechanism
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Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
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