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注意:仅列出部分参考文献,下载原文获取全部文献信息。The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
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NUCLEIC ACIDS RESEARCH (2018)
The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations
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BRITISH JOURNAL OF PHARMACOLOGY (2017)
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NATURE REVIEWS ENDOCRINOLOGY (2017)
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Akiko Sankoda et al.
ENDOCRINOLOGY (2017)
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Mustafa A. Karwad et al.
FASEB JOURNAL (2017)
Peripheral tissue levels and molecular species compositions of N-acyl-phosphatidylethanolamine and its metabolites in mice lacking N-acyl-phosphatidylethanolamine-specific phospholipase D
Manami Inoue et al.
JOURNAL OF BIOCHEMISTRY (2017)
Gq and Gs signaling acting in synergy to control GLP-1 secretion
Maria Hauge et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
Commensal bacteria make GPCR ligands that mimic human signalling molecules
Louis J. Cohen et al.
NATURE (2017)
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Adele Romano et al.
PHARMACOLOGICAL RESEARCH (2017)
Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling
Gernot F. Grabner et al.
PHARMACOLOGY & THERAPEUTICS (2017)
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Jacob D. Brown et al.
PHYSIOLOGY & BEHAVIOR (2017)
Oleic acid-derived oleoylethanolamide: A nutritional science perspective
Kate J. Bowen et al.
PROGRESS IN LIPID RESEARCH (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
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Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
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Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Chylomicrons stimulate incretin secretion in mouse and human cells
Arianna Psichas et al.
DIABETOLOGIA (2017)
Mammalian enzymes responsible for the biosynthesis of N-acylethanolamines
Zahir Hussain et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)
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Pegah Poursharifi et al.
DIABETES OBESITY & METABOLISM (2017)
A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner
Sally Miller et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
GPCR-Mediated Signaling of Metabolites
Anna Sofie Husted et al.
CELL METABOLISM (2017)
Duodenal fatty acid sensor and transporter expression following acute fat exposure in healthy lean humans
Nada Cvijanovic et al.
CLINICAL NUTRITION (2017)
Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats
Mohammed K. Hankir et al.
CELL METABOLISM (2017)
The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels
Stefania Petrosino et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
N-Acylethanolamines Bind to SIRT6
Minna Rahnasto-Rilla et al.
CHEMBIOCHEM (2016)
Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119
Helle A. Hassing et al.
BIOCHEMICAL PHARMACOLOGY (2016)
Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor
H. A. Hassing et al.
BIOFACTORS (2016)
Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet
Bo Wang et al.
CELL METABOLISM (2016)
GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40)
Jeppe H. Ekberg et al.
ENDOCRINOLOGY (2016)
A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines
Yuji Ogura et al.
NATURE CHEMICAL BIOLOGY (2016)
Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells
Daryl Hodge et al.
PEPTIDES (2016)
Upper gastrointestinal sensitivity to meal-related signals in adult humans - relevance to appetite regulation and gut symptoms in health, obesity and functional dyspepsia
Christine Feinle-Bisset
PHYSIOLOGY & BEHAVIOR (2016)
Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR--Dependent Inhibition of Akt/mTOR Pathway
Giovanni Sarnelli et al.
PHYTOTHERAPY RESEARCH (2016)
Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function
Ji-Won Lee et al.
NATURE COMMUNICATIONS (2016)
Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation
Silvia Pontis et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans
Mette J. Mandoe et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2015)
Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents
Miki Igarashi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)
N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis
Mireille Alhouayek et al.
FASEB JOURNAL (2015)
Modulation of Glucagon-like Peptide-1 (GLP-1) Potency by Endocannabinoid-like Lipids Represents a Novel Mode of Regulating GLP-1 Receptor Signaling
Yu-Hong Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Gut chemosensing mechanisms
Arianna Psichas et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Intestinal lipid-derived signals that sense dietary fat
Nicholas V. DiPatrizio et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity
John D. Douglass et al.
JOURNAL OF LIPID RESEARCH (2015)
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol
Karen Kleberg et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity
Lauren M. Cornall et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
Endocannabinoids are conserved inhibitors of the Hedgehog pathway
Helena Khaliullina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Thematic Review Series: Intestinal Lipid Metabolism: New Developments and Current Insights Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism
Chi-Liang Eric Yen et al.
JOURNAL OF LIPID RESEARCH (2015)
Dietary Triacylglycerols with Palmitic Acid in the sn-2 Position Modulate Levels of N-Acylethanolamides in Rat Tissues
Gianfranca Carta et al.
PLOS ONE (2015)
Gas1 is a receptor for sonic hedgehog to repel enteric axons
Shiying Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine
Louise W. Christensen et al.
PHYSIOLOGICAL REPORTS (2015)
Vagal afferents are not necessary for the satiety effect of the gut lipid messenger oleoylethanolamide
Elnaz Karimian Azari et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2014)
Evaluation of the immediate vascular stability of lipoprotein lipase-generated 2-monoacylglycerol in mice
Karen Kleberg et al.
BIOFACTORS (2014)
Classical endocannabinoid-like compounds and their regulation by nutrients
Karen Kleberg et al.
BIOFACTORS (2014)
Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB1 receptors and TRPV1 channels
Raffaele Capasso et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation
Giuseppe Esposito et al.
GUT (2014)
Intestine-specific Deletion of Acyl-CoA: Monoacylglycerol Acyltransferase (MGAT) 2 Protects Mice from Diet-induced Obesity and Glucose Intolerance
David W. Nelson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis
Yan-Wei Hu et al.
JOURNAL OF LIPID RESEARCH (2014)
Endogenous Ceramide Contributes to the Transcytosis of oxLDL across Endothelial Cells and Promotes Its Subendothelial Retention in Vascular Wall
Wenjing Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Dietary Non-Esterified Oleic Acid Decreases the Jejunal Levels of Anorectic N-Acylethanolamines
Thi Ai Diep et al.
PLOS ONE (2014)
Modulation of T-type calcium channels by bioactive lipids
Jean Chemin et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat
Harald S. Hansen
PHARMACOLOGICAL RESEARCH (2014)
Effect of Diet on Tissue Levels of Palmitoylethanolamide
Harald S. Hansen
CNS & Neurological Disorders-Drug Targets (2013)
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
Stephen G. Young et al.
GENES & DEVELOPMENT (2013)
A Gut Lipid Messenger Links Excess Dietary Fat to Dopamine Deficiency
Luis A. Tellez et al.
SCIENCE (2013)
A fatty gut feeling
Daniele Piomelli
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines
Oleg I. Voitychuk et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice
M. Bashashati et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Peroxisome Proliferator-Activated Receptor α Mediates Acute Effects of Palmitoylethanolamide on Sensory Neurons
Iryna A. Khasabova et al.
JOURNAL OF NEUROSCIENCE (2012)
Regulation of fat intake in the absence of flavour signalling
Jozelia G. Ferreira et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
GPR119 as a fat sensor
Harald S. Hansen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor
Thi Ai Diep et al.
FASEB JOURNAL (2011)
2-Oleoyl Glycerol Is a GPR119 Agonist and Signals GLP-1 Release in Humans
Katrine B. Hansen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase
Jonathan Z. Long et al.
JOURNAL OF LIPID RESEARCH (2011)
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents
X. -H. Lin et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
Peroxisome Proliferator-Activated Receptors-Alpha Modulate Dopamine Cell Activity Through Nicotinic Receptors
Miriam Melis et al.
BIOLOGICAL PSYCHIATRY (2010)
Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner
Adriana Barana et al.
CARDIOVASCULAR RESEARCH (2010)
FAAH deficiency promotes energy storage and enhances the motivation for food
C. Tourino et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner
Irene Amoros et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
CD36 gene deletion decreases oleoylethanolamide levels in small intestine of free-feeding mice
Ana Guijarro et al.
PHARMACOLOGICAL RESEARCH (2010)
GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis
Hong Lan et al.
JOURNAL OF ENDOCRINOLOGY (2009)
Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats
Jin Fu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine
Andreas Artmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
The Lipid Messenger OEA Links Dietary Fat Intake to Satiety
Gary J. Schwartz et al.
CELL METABOLISM (2008)
Monoacylglycerols activate capsaicin receptor, TRPV1
Yusaku Iwasaki et al.
LIPIDS (2008)
The orphan receptor GPR55 is a novel cannabinoid receptor
E. Ryberg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine
Jin Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A second fatty acid amide hydrolase with variable distribution among placental mammals
Binqing Q. Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors
G Petersen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)
Endogenous unsaturated C18N-acylethanolamines are vanilloid receptor (TRPV1) agonists
P Movahed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The metabolism of structured triacylglycerols
HL Mu et al.
PROGRESS IN LIPID RESEARCH (2005)
Fatty acid amide hydrolase controls mouse intestinal motility in vivo
R Capasso et al.
GASTROENTEROLOGY (2005)
Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity
K Proulx et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
Uptake of micellar long-chain fatty acid and sn-2-monoacylglycerol into human intestinal Caco-2 cells exhibits characteristics of protein-mediated transport
K Murota et al.
JOURNAL OF NUTRITION (2005)
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597):: Effects on anandamide and oleoylethanolamide deactivation
D Fegley et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
J Lo Verme et al.
MOLECULAR PHARMACOLOGY (2005)
Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor α (PPAR-α)
M Guzmán et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Occurrence, metabolism, and prospective functions of N-acylethanolamines in plants
KD Chapman
PROGRESS IN LIPID RESEARCH (2004)
Food intake is inhibited by oral oleoylethanolamide
MJ Nielsen et al.
JOURNAL OF LIPID RESEARCH (2004)
Oleoylethanolamide inhibits food intake in free-feeding rats after oral administration
F Oveisi et al.
PHARMACOLOGICAL RESEARCH (2004)
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
J Fu et al.
NATURE (2003)
Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide
S Gaetani et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans
C Feinle et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
An anorexic lipid mediator regulated by feeding
FR de Fonseca et al.
NATURE (2001)