期刊
BONE
卷 111, 期 -, 页码 23-27出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.bone.2018.03.007
关键词
Calcium; Dietary supplements; Trends
资金
- NIH National Heart, Lung, and Blood Institute [R01-HL103706, T32-HL-007779]
- Office of Dietary Supplements [R01-HL103706-S1]
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL103706, T32HL007779] Funding Source: NIH RePORTER
Background: Long-term outcomes of supplemental calcium are inadequately understood. Recent research suggests that calcium from supplements may not be entirely free from unintended health consequences. Consequently, it is important to understand patterns and trends in use of calcium supplements. Objective: To report trends in supplemental calcium intake between 1999 and 2014, using NHANES data, overall and stratified by sex, race/ethnicity and age. Methods: A total of 42,038 adult NHANES participants were included in this analysis. For each survey period, we calculated the prevalence of calcium supplement use exceeding the Estimated Average Requirement (EAR) and Tolerable Upper Intake Levels (UL), and mean daily supplemental calcium dose among calcium-containing supplement users. Sample weights were applied. Linear regression was used to examine trends. Results: Overall, the prevalence of calcium supplement use at a dose >= EAR increased between 1999 and 2000 and 2013-2014, from 2.5% (95% CI: 1.9-3.3%) to 4.6% (3.8-5.5%). Use >= EAR peaked in 2003-2004 at 6.7% (5.3-8.5%) (p-quadratic trend < 0.001). Mean supplemental calcium intake peaked in 2007-2008, thereafter decreasing (p-quadratic trend < 0.001). The overall prevalence of intake >= UL. from supplemental calcium in 2013-2014 was 0.4% (0.2-0.8%). Use of supplemental calcium >= UL peaked during 2007-2008 at 1.2% (0.7-2.0%). in all time periods, supplemental calcium intake tended to be greater among women, non-Hispanic whites and adults >60 years. Conclusions: We described the prevalence of U.S. adults consuming supplemental calcium >= UL and >= EAR. While few were consuming supplemental calcium >= UL, consumption >= EAR was not uncommon, especially among women, non-Hispanic whites and older adults. (C) 2018 Elsevier Inc All rights reserved.
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