期刊
BIOSENSORS & BIOELECTRONICS
卷 112, 期 -, 页码 143-148出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2018.03.020
关键词
18-facet polyhedron Cu7S4 nanocrystals; CuS sphere; CuS flower; H2O2; Prostate specific antigen
类别
资金
- Shandong Provincial Natural Science Foundation of China [ZR2016BM01]
- National Natural Science Foundation of China [21575050, 21375047]
18-facet polyhedron Cu7S4 nanocrystal and CuS sphere were prepared from Cu2O precursor, and CuS flower was synthesized through a simple solvothermal approach. Their electrochemical performances were investigated towards H2O2 and it was interesting to discover that Cu7S4 nanocrystal had the best electrochemical catalysis compared with CuS sphere and CuS flower. It can deduce that the special structure of Cu7S4 nanocrystal endowed it more exposed active points, higher surface area and higher Cu/S ratio. Therefore, Cu7S4 nanocrystal was firstly employed to prepare a nonenzymatic biosensor for H2O2. Satisfactory results were obtained. In addition, a label-free sensing platform for prostate specific antigen (PSA) was constructed based on electrochemical catalysis towards H2O2 of Cu7S4 nanocrystal. The label-free immunosenosr offered accurate PSA in the range of 0.001-15 ng/mL with the detection limit of 0.001 ng/mL. Besides, the immunosensor possessed good sensitivity, selectivity and stability and could detect PSA in real sample. More importantly, this work demonstrated that Cu7S4 nanocrystal hold great promising application in electrochemical sensors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据