期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 82, 期 8, 页码 1404-1407出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2018.1465811
关键词
Group I intron; polyamine; polyethylene polyamine; ribozyme
类别
资金
- Grants-in-Aid for Scientific Research [15K05561] Funding Source: KAKEN
Polyamines are a promising class of molecules that can modulate RNA enzyme activities. To analyze the effects of the number of amine moieties systematically, we employed four polyamines sharing dimethylene units to connect amine moieties. As a model RNA enzyme, we used a structurally unstable group I ribozyme, which was activated most and least efficiently by tetraethylenepentamine and diethylenetriamine respectively.
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