期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 17, 期 3, 页码 -出版社
MDPI AG
DOI: 10.3390/ijms17030131
关键词
foamy macrophage; tuberculosis; granuloma; mycobacterium
资金
- National Research Foundation
- Kwa-Zulu Natal Research Institute for Tuberculosis and HIV
- College of Health Sciences, University of Kwa-Zulu Natal
Mycobacterium tuberculosis (MTB) is one of the most successful pathogens in human history and remains a global health challenge. MTB has evolved a plethora of strategies to evade the immune response sufficiently to survive within the macrophage in a bacterial-immunological equilibrium, yet causes sufficient immunopathology to facilitate its transmission. This review highlights MTB as the driver of disease pathogenesis and presents evidence of the mechanisms by which MTB manipulates the protective immune response into a pathological productive infection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据