期刊
BIOLOGICAL CHEMISTRY
卷 399, 期 2, 页码 101-125出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/hsz-2017-0137
关键词
cis/trans isomerization; parvulin; Par14; Par17; Pin1; PPIase
资金
- Deutsche Forschungsgemeinschaft (DFG) [BA-1431/1-3]
Parvulins belong to the family of peptidyl-prolyl cis/trans isomerases (PPIases) assisting in protein folding and in regulating the function of a broad variety of proteins in all branches of life. The human representatives Pin1 and Par14/17 are directly involved in processes influencing cellular maintenance and cell fate decisions such as cell-cycle progression, metabolic pathways and ribosome biogenesis. This review on human parvulins summarizes the current knowledge of these enzymes and intends to oppose the well-studied Pin1 to its less well-examined homolog human Par14/17 with respect to structure, catalytic and cellular function.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据