期刊
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
卷 50, 期 -, 页码 72-83出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2018.04.001
关键词
Endometriosis; Diagnosis; Biomarker; Peripheral blood; Endometrium; Systems biology
资金
- Research Foundation -Flanders (FWO) [11X5517N]
A noninvasive biomarker-based test could help shorten the diagnostic delay for endometriosis. The most investigated biomarker sources are peripheral blood and endometrium. Discovery of endometriosis biomarkers is often hypothesis-driven, i.e. when one or a few biomarkers are investigated based on their role in the disease pathogenesis. Alternatively, a hypothesis-generating approach has been followed using the omics technologies. A variety of biomarkers for endometriosis have been investigated, but no biomarker has been validated for clinical use. Many challenges lie ahead in the endometriosis biomarker field. In the future, harmonized collection and reporting methods should allow large-scale international collaboration for highly powered studies. (C) 2018 Published by Elsevier Ltd.
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