期刊
ACM SIGPLAN NOTICES
卷 51, 期 4, 页码 637-649出版社
ASSOC COMPUTING MACHINERY
DOI: 10.1145/2872362.2872397
关键词
Archival storage; molecular computing; DNA
资金
- NSF [1064497, 1409831]
- David Notkin Endowed Graduate Fellowship
- Direct For Computer & Info Scie & Enginr
- Division of Computing and Communication Foundations [1409831, 1064497] Funding Source: National Science Foundation
Demand for data storage is growing exponentially, but the capacity of existing storage media is not keeping up. Using DNA to archive data is an attractive possibility because it is extremely dense, with a raw limit of 1 exabyte/mm(3) (10(9) GB/mm(3)), and long-lasting, with observed half-life of over 500 years. This paper presents an architecture for a DNA-based archival storage system. It is structured as a key-value store, and leverages common biochemical techniques to provide random access. We also propose a new encoding scheme that offers controllable redundancy, trading off reliability for density. We demonstrate feasibility, random access, and robustness of the proposed encoding with wet lab experiments involving 151 kB of synthesized DNA and a 42 kB random-access subset, and simulation experiments of larger sets calibrated to the wet lab experiments. Finally, we highlight trends in biotechnology that indicate the impending practicality of DNA storage for much larger datasets.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据