4.5 Article

E. coli MG1655 modulates its phospholipid composition through the cell cycle

期刊

FEBS LETTERS
卷 589, 期 19, 页码 2726-2730

出版社

WILEY
DOI: 10.1016/j.febslet.2015.07.043

关键词

Lipid; Lipidomic; Cell cycle; Cell cycle control; Lipid metabolism

资金

  1. research programme of the bio-based ecologically balanced sustainable industrial chemistry (BE-BASIC)
  2. Dutch organisation for scientific research De Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO)

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This paper describes a study of the phospholipid profile of Escherichia coli MG1655 cultures at the B and D periods of the cell cycle. The results indicate that the phosphatidyl glycerol fraction grows relatively rapidly and that the size of the cardiolipin (CL) fraction does not grow at all during cell elongation. This is consistent with observations that CL is located preferentially at the poles of E. coli. It also suggests that lipid production is controlled as a function of the cell cycle. (C) 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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